BENZALKONIUM CHLORIDE

Molecular Excipient

Mwt. LogP HBD HBA PSA RB CSP3
319.0 6.6 0 0 0.0 14 0.73
UNII
F5UM2KM3W7
CAS
8001545
ZINC ID(s)
Availability
Present in 10 ZINC catalogs

Known Active Genes

There has not been any activity reported at 10μM or less for this excipient (per ChEBML)

Clinical Trials

This compound has been an intervention in the following clincial trials (per clinicaltrials.gov).
Code Date Title Phase Status
NCT00414739 Testing of Innocuousness of Benzalkonium Chloride on the Eye Concerning Possible Growth of Langerhans Cells Phase 1 Recruiting
NCT02269800 2014-10-01 An Efficacy Study of BCS Clearing the Oral Colonized Bacterium in Hospitalized Patients With COPD Phase 4 Not Yet Recruiting
NCT00845299 2009-01-01 Study of the Effects of Artificial Tears on the Response to the Latanoprost Punctal Plug Delivery System in Subjects With Ocular Hypertension or Open-Angle Glaucoma Phase 2 Completed
NCT00692952 2004-03-01 Effectiveness of BenZalkonium Chloride Gel as Vaginal Contraceptive: a Multicentric Randomized Controlled Trial Phase 2 Completed

(Browse) Purchasable Analogs in ZINC

Products Using Benzalkonium Chloride

Brand (Manufacturer) Generic Name (Route)
Rx Act Nasal Sinus (H E B) Oxymetazoline Hydrochloride (NASAL)
Eye Drops Sy (KC Pharmaceuticals, Inc.) Polyethylene Glycol 400, Propylene Glycol (OPHTHALMIC)
Afrin No Drip Sinus Pump Mist (MSD Consumer Care, Inc.) Oxymetazoline Hydrochloride (NASAL)
Leader Relief (HANLIM PHARM. CO., LTD.) Tetrahydrozoline Hydrochloride And Zinc Sulfate (OPHTHALMIC)
Hand-E-Foam (DermaRite Industries, LLC) Otc Antimicrobial Drug Products (TOPICAL)
Esika Total Sec Ultra Fresh (Ventura Corporation, Ltd.) Aluminum Sesquichlorohydrate (TOPICAL)
Leader Advanced Formula Eye Drops (HANLIM PHARM. CO., LTD.) Dextran 70 (OPHTHALMIC)
Ambi Even And Clear Daily Moisturizer Sunscreen Broad Spectrum Spf30 (Valeant Pharmaceuticals North America LLC) Avobenzone, Homosalate, Octisalate, Octocrylene, And Oxybenzone (TOPICAL)
12 Hour Nasal (Meijer Distribution Inc) Oxymetazoline Hydrochloride (NASAL)
Advanced Eye Relief Dry Eye Rejuvenation (Bausch & Lomb Incorporated) Glycerin Propylene Glycol (OPHTHALMIC)
Eye Drops Regular (McKesson) Tetrahydrozoline Hydrochloride (OPHTHALMIC)
First Aid Contains 101 Pieces (Genuine First Aid LLC) Benzalkonium Chloride, Lidocaine, Water, Isopropyl Alcohol, Aspirin (None)
Oil Free Acne Scrub Salicylic Acid Acne Treatment (Apex International Mfg) Salicylic Acid (TOPICAL)
Dg Health Sterile Redness Relief (Dolgencorp Inc) Tetrahydrozoline Hydrochloride (OPHTHALMIC)
Good Neighbor Pharmacy Itchy Eye (Amerisource Bergen) Ketotifen (OPHTHALMIC)
Neo-Synephrine Cold And Sinus Regular Strength (Bayer HealthCare Consumer Care) Phenylephrine Hydrochloride (NASAL)
Opticlear (Major Pharmaceuticals) Tetrahydrozoline Hcl (OPHTHALMIC)
Neutrogena Rapid Clear 2 In 1 Fight And Fade Toner (Johnson & Johnson Consumer Inc.) Salicylic Acid (TOPICAL)
Equate Enema (Wal-Mart Stores Inc) Saline (RECTAL)
Zicam Allergy Relief (Matrixx Initiatives, Inc.) Galphimia Glauca Flowering Top, Histamine Dihydrochloride, Luffa Operculata Fruit, And Sulfur (NASAL)
Tears Lubricant (Navarro Discount Pharmacies,LLC) Glycerin, Hypromellose, Polyethylene Glycol 400 (OPHTHALMIC)
Itchy Eye (Meijer Distribution Inc) Ketotifen Fumarate (OPHTHALMIC)
Nasal Mist (Shopko Stores Operating Co., LLC) Oxymetazoline Hcl (NASAL)
Esika Salvaje Roll-On (Ventura Corporation Ltd.) Aluminum Sesquichlorohydrate (TOPICAL)
Enema (Meijer Distribution Inc) Saline (RECTAL)
Acnefree Severe Terminator Maximum Strength (Valeant Pharmaceuticals North America LLC) Benzoyl Peroxide (TOPICAL)
Rohto Arctic (The Mentholatum Company) Hypromellose, Tetrahydrozoline Hydrochloride (OPHTHALMIC)
Neutrogena Men Sensitive Skin Oil Free Moisture Sunscreen Broad Spectrum Spf30 (Neutrogena Corporation) Avobenzone, Homosalate, Octisalate, Octocrylene, And Oxybenzone (TOPICAL)
Oil-Free Acne Wash (Harmon Stores Inc) Salicylic Acid (TOPICAL)
Nasal Relief 12-Hour (Rugby Laboratories) Oxymetazoline Hydrochloride (NASAL)
Acnefree Clear Skin Treatments 24 Hour Severe Acne Clearing System (Valeant Pharmaceuticals North America LLC) Benzoyl Peroxide (None)
Equaline Nasal (Supervalu Inc) Oxymetazoline Hydrochloride (NASAL)
Neutrogena Oil Free Acne Wash Pink Grapefruit Facial Cleanser (Neutrogena Corporation) Salicylic Acid (TOPICAL)
Up And Up Ready To Use Enema (Target Corporation) Dibasic Sodium Phosphate, Monobasic Sodium Phosphate (RECTAL)
Preferred Plus 12 Hour Nasal Original (Kinray) Oxymetazoline Hydrochloride (NASAL)
Cvs Pharmacy Illuminating (CVS PHARMACY) Avobenzone, Octinoxate, Octisalate (TOPICAL)
Zicam Allergy Relief (Matrixx Initiatives, Inc.) Galphimia Glauca Flowering Top, Histamine Dihydrochloride, Luffa Operculata Fruit, And Sulfur (NASAL)
Neutrogena Body Clear Body (Johnson & Johnson Consumer Inc.) Salicylic Acid (TOPICAL)
Nasal (Kroger Company) Oxymetazoline Hcl (NASAL)
Aveeno Baby Eczema Therapy Moisturizing (Johnson & Johnson Consumer Inc.) Oatmeal (TOPICAL)
Procomycin (Aidarex Pharmaceuticals LLC) Bacitracin, Neomycin, Polymyxin B And Lidocain Hydrochloride (TOPICAL)
Arc First Aid Contains 404 Pieces (American Red Cross) Benzalkonium Chloride, Lidocaine, Water, Bacitracin Zinc, Neomycin Sulfate, Polymyxin B Sulfate, Water, Isopropyl Alcohol, Benzocaine, Alcohol, Aspirin (None)
Leader Lubricating Eye (CARDINAL HEALTH) Carboxymethylcellulose Sodium, And Glycerin (OPHTHALMIC)
Natureplex Enema (Natureplex, LLC) (saline) (RECTAL)
Simple Saline Cold Formula Plus Menthol (Church & Dwight Co., Inc.) Luffa Operculata, Sabadilla (NASAL)
Up And Up Nasal (Target Corporation) Oxymetazoline Hydrochloride (NASAL)
Hypotears (Novartis Pharmaceutical Corporation) Polyvinyl Alcohol And Polyehtylene Glycol 400 (OPHTHALMIC)
Rite Aid Daily Moisturizer Spf 15 (Rite Aid Corporation) Avobenzone (TOPICAL)
Neo-Synephrine Cold And Sinus Extra Strength (Bayer HealthCare Consumer Care) Phenylephrine Hydrochloride (NASAL)
Neutrogena Oil Free Acne Correct And Cover Pink Grapefruit Moisturizer Medium To Tan (Johnson & Johnson Consumer Inc.) Salicylic Acid (TOPICAL)
First Aid Contains 404 Pieces (Genuine First Aid LLC) Benzalkonium Chloride, Lidocaine, Water, Isotropyl Alcohol, Benzocaine, Alcohol, Aspirin (None)
Aveeno Eczema Therapy Moisturizing (Johnson & Johnson Consumer Products Company, Division of Johnson & Johnson Consumer Companies, Inc.) Oatmeal (TOPICAL)
Optical Advanced Eye (TELEVISA CONSUMER PRODUCTS USA) Dextran 70, Polyethylene Glycol 400, Povidone, Tetrahydrozoline Hcl (OPHTHALMIC)
Nasal Decongestant (Safeway) Oxymetazoline Hydrochloride (NASAL)
Nasal (Shopko Stores Operating Co., LLC) Oxymetazoline Hcl (NASAL)
Nyloxin (Receptopharm Inc.) Naja Naja Venom (TOPICAL)
Rx Act Nasal Four (H E B) Phenylephrine Hydrochloride (NASAL)
Afrin Original Pump Mist (MSD Consumer Care, Inc.) Oxymetazoline Hydrochloride (NASAL)
Arc First Aid Contains 303 Pieces Hardcase (American Red Cross) Benzalkonium Chloride, Lidocaine, Bacitracin Zinc, Neomycin Sulfate, Polymyxin B Sulfatebacitracin Zinc, Neomycin Sulfate, Polymyxin B Sulfate, Water, Isopropyl Alcohol,benzocaine,alcohol, Aspirin (None)
Acme First Aid Contains 404 Pieces (Acme United Corp.) Benzalkonium Chloride, Lidocaine, Water, Isopropyl Alcohol, Aspirin, Benzocaine, Alcohol, Bacitracin Zinc, Neomycin Sulfate, Polymyxin B Sulfate (None)
Eye Allergy Relief (Rite Aid Corporation) Pheniramine Maleate And Naphazoline Hydrochloride (OPHTHALMIC)
Sinusin (Biologische Heilmittel Heel) Silver Nitrate, Euphorbia Resinifera Resin, Calcium Sulfide, Luffa Operculata Fruit, Mercuric Iodide, Sus Scrofa Nasal Mucosa, Pulsatilla Vulgaris And Sinusitisinum (NASAL)
Rohto Cool Max (Rohto Pharmaceutical Co. Ltd.) Naphazoline Hydrochloride, Polysorbate 80 (OPHTHALMIC)
Wal Zyr (Walgreen Company) Ketotifen (OPHTHALMIC)
Good Sense Nasal (L Perrigo Company) Oxymetazoline Hcl (NASAL)
Extra Moisturizing (Publix Super Markets Inc) Oxymetazoline Hcl (NASAL)
Clear Eyes Triple Action (Prestige Brands Holdings, Inc.) Polyvinyl Alcohol And Povidone And Tetrahydrozoline Hydrochloride (OPHTHALMIC)
Ketotifen Fumarate (Akorn, Inc.) Ketotifen Fumarate (OPHTHALMIC)
No Drip (Publix Super Markets Inc) Oxymetazoline Hcl (NASAL)
Walgreens Sterile Advance Relief Eye Drops (Walgreen Company) Dextran, Polyethylene Glycol, Povidone, Tetrahydrozoline Hydrochloride (OPHTHALMIC)
Wal Four (Walgreen Company) Phenylephrine Hydrochloride (NASAL)
Xpect Buffered Eyewash Sterile Isotonic (Cintas) Water (OPHTHALMIC)
Topcare Daily Moisturizer For Face (Topco Associates LLC) Avobenzone, Octinoxate,octisalate (TOPICAL)
Advanced Relief (Samchundang Pharm. Co., Ltd.) Dextran 70, Polyethylene Glycol 400, Povidone, Tetrahydrozoline Hcl (OPHTHALMIC)
Nasal Decongestant (Safeway) Oxymetazoline Hcl (NASAL)
Neutrogena Oil Free Acne Wash Redness Soothing Cream Cleanser (Neutrogena Corporation) Salicylic Acid (TOPICAL)
Advanced Relief (Kareway Product, Inc.) Dextran 70, Polyethylene Glycol 400, Povidone, Tetrahydrozoline Hcl (OPHTHALMIC)
Neo-Synephrine Cold And Sinus Regular Strength (Foundation Consumer Healthcare LLC) Phenylephrine Hydrochloride (NASAL)
Visine A.c. (Johnson & Johnson Consumer Inc.) Tetrahydrozoline Hydrochloride And Zinc Sulfate (OPHTHALMIC)
Mucinex Nasal Full Force (Reckitt Benckiser, Inc.) Oxymetazoline Hydrochloride (NASAL)
Walgreens Maximum Relief Eye Drops (HANLIM PHARM. CO., LTD.) Dextran 70 (OPHTHALMIC)
Esika Danzzia Roll-On (Ventura Corporation LTD.) Aluminum Sesquichlorohydrate (TOPICAL)
Smart Sense Enema (Kmart Corporation) Saline (RECTAL)
Original (Publix Super Markets Inc) Oxymetazoline Hydrochloride (NASAL)
Neutrogena Skinclearing Mineral - Buff (Neutrogena Corporation) Salicylic Acid (TOPICAL)
Walgreens Maximum Redness Relief (WALGREEN COMPANY) Glycerin, Naphazoline Hydrochloride (OPHTHALMIC)
Manzanilla Sophia (Teresa Cecena DBA Genesis) Matricaria Recutita (OPHTHALMIC)
Smart Sense Sinus Relief (Kmart Corporation) Oxymetazoline Hcl (NASAL)
Therabiogen Cold And Flu Relief Nasal (THERABIOGEN) Camelia Sinensis, Sambucus Nigra, Gelsemium Sempervirens, Bryonia Alba, Sulphur (NASAL)
Antiseptic (Safetec of America, Inc.) Alcohol, Benzocaine (TOPICAL)
Neutrogena Oil-Free Acne Wash Pink Grapefruit Foaming Scrub (Johnson & Johnson Consumer Inc.) Salicylic Acid (TOPICAL)
Clean And Clear Morning Glow Moisturizer Sunscreen Broad Spectrum Spf 15 (Johnson & Johnson Consumer Products Company, Division of Johnson & Johnson Consumer Companies, Inc.) Avobenzone, Octinoxate, And Octisalate (TOPICAL)

Dosages

Route Formulation Per Unit Dose
Ophthalmic Gel 0.01%
Auricular (otic) Solution 0.03%
Auricular (otic) Suspension 0.02%
Inhalation Solution 20%
Inhalation Spray 0.0002%
Intra-Articular Injectable 0.02%
Intra-Articular Injection 0.01%
Intra-Articular Suspension 0.01%
Intrabursal Injection
Intradermal Injection
Intralesional Injectable 0.02%
Intralesional Injection
Intramuscular Injectable 0.02%
Intramuscular Injection 0.01%
Intramuscular Suspension 0.01%
Intraocular Solution 0.01%
Intrasynovial Injection 0.01%
Nasal Gel
Nasal Solution 1%
Nasal Solution, Spray 0.03%
Nasal Spray 0.12%
Nasal Spray, Metered 0.01%W/V
Ophthalmic Drops 0.0004%
Ophthalmic Ointment 0.03%
Ophthalmic Solution 40%
Ophthalmic Solution, Drops 0.9%
Ophthalmic Solution/drops 0.01%
Ophthalmic Suspension 0.03%
Ophthalmic Suspension, Drops 0.03%
Oral Solution 0.02%
Respiratory (inhalation) Solution, Spray 0.0002%
Respiratory (inhalation) Spray 0.01%
Topical Jelly
Topical Lotion 0.1%
Topical Shampoo 0.2%
Topical Solution 0.02%W/V
Topical Solution, Drops 0.02%W/V
Topical Suspension 0.01%

More Information

Usage Over Time

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