DIMETHICONE

Molecular Excipient

Mwt. LogP HBD HBA PSA RB CSP3
162.0 2.7 0 1 9.0 2 1.0
UNII
92RU3N3Y1O
CAS
9006-65-9
SYNONYMS
  • Dimethicone
  • Dimethyl Polysiloxane
  • Dimethicone 360
  • Polydimethylsiloxane
  • Poly(dimethylsiloxane)
  • Dimeticone
  • Dimeticone [inn]
  • Dimethicone [usan]
  • Dimeticone [ep]
  • Dimethicone Component Of Simethicone
  • Simethicone Component Dimethicone
  • Dimethicone (14000-21000 Mw)
  • Dimethicone (300-600 Mpa.s)
  • Dimethicone (300-600 Cps)
  • Dimeticone [jan]
  • Sentry Dimethicone
  • Dimethylpolysiloxane
  • Dimethicone [inci]
  • Dimethylpolysiloxane [fcc]
  • Dimeticone [mart.]
  • Dimethicones
  • Dimethicone 360 [ii]
  • Dimethicone Medical Fluid 360
  • Dimeticone [who-Dd]
  • Dimethicone [vandf]
  • Dimeticone-360
  • Dimethicone [mi]
  • E-900a
  • Ins-900a
  • Ins No.900a
  • Dimethylsilicone Oil
  • Dimethylsilicone Fluid
  • Silkonoel Ak 500
ZINC ID(s)
Availability
Present in 13 ZINC catalogs

Known Active Genes

There has not been any activity reported at 10μM or less for this excipient (per ChEBML)

Clinical Trials

This compound has been an intervention in the following clincial trials (per clinicaltrials.gov).
Code Date Title Phase Status
NCT01914627 2013-08-01 Parallel Group Trial to Evaluate the Efficacy and Safety of Loion® Compared to 10% Salicylic Acid in Patients With Chronic Psoriasis Capitis Phase 2 Completed

(Browse) Purchasable Analogs in ZINC

Products Using Dimethicone

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APIs Products incorporating these APIs
Fluorouracil Fluorouracil(RX) , Fluorouracil(RX)
Capsaicin Qutenza(RX) , Qutenza(RX)
Budesonide Budesonide(RX) , Budesonide(RX) , Budesonide(RX) , Budesonide(RX)
Cephalexin Keflex(DISCN) , Cephalexin(DISCN) , Keflex(DISCN)
Fenofibrate Fenofibrate(RX) , Antara(RX)
Triamcinolone Acetonide Triamcinolone Acetonide(RX) , Triamcinolone Acetonide(RX) , Triamcinolone Acetonide(RX)
Dabigatran Etexilate Mesylate Pradaxa(RX) , Pradaxa(RX)
Clindamycin Phosphate And Benzoyl Peroxide Neuac Kit(RX)
Dipyridamole , Aspirin Aspirin And Dipyridamole(RX) , Aggrenox(RX) , Aspirin And Dipyridamole(RX) , Aggrenox(RX) , Aggrenox(RX) , Aggrenox(RX)
Loperamide Hydrochloride Loperamide Hydrochloride(RX) , Loperamide Hydrochloride(RX) , Loperamide Hydrochloride(RX) , Loperamide Hydrochloride(RX) , Loperamide Hydrochloride(RX) , Loperamide Hydrochloride(RX) , Loperamide Hydrochloride(RX) , Loperamide Hydrochloride(RX) , Loperamide Hydrochloride(RX) , Loperamide Hydrochloride(RX) , Loperamide Hydrochloride(RX) , Loperamide Hydrochloride(RX) , Loperamide Hydrochloride(RX) , Loperamide Hydrochloride(RX) , Loperamide Hydrochloride(RX) , Loperamide Hydrochloride(RX) , Loperamide Hydrochloride(RX) , Loperamide Hydrochloride(RX)
Econazole Nitrate Ecoza(RX)
Ivermectin Soolantra(RX)
Olanzapine , Fluoxetine Hydrochloride Symbyax(RX)
Ecamsule , Octocrylene , Avobenzone La Roche Posay Laboratoire Dermatologique Anthelios Sx Daily Moisturizing Sunscreen Broad Spectrum Spf 15(OTC)
Chlorhexidine Gluconate , Alcohol 3m Avagard(OTC)
Chlorhexidine Gluconate Skin Antisepsis, Oral Cleansing, Nasal Antisepsis(OTC)
Hydrocortisone Acetate , Pramoxine Hydrochloride Pramosone(RX) , Pramosone(RX) , Analpram Hc(RX)
Eflornithine Hydrochloride Vaniqa(RX)
Pancrelipase Lipase , Pancrelipase Protease , Pancrelipase Amylase Creon(RX) , Creon(RX) , Creon(RX) , Creon(RX) , Creon(RX)
Nizatidine Nizatidine(RX) , Nizatidine(RX) , Nizatidine(RX)
Fluticasone Propionate Fluticasone Propionate(RX) , Fluticasone Propionate(RX) , Cutivate(RX)
Nortriptyline Hydrochloride Nortriptyline Hydrochloride(RX) , Nortriptyline Hydrochloride(RX) , Nortriptyline Hydrochloride(RX) , Nortriptyline Hydrochloride(RX) , Nortriptyline Hydrochloride(RX) , Nortriptyline Hydrochloride(RX) , Nortriptyline Hydrochloride(RX)
Crotamiton Eurax(RX)
Clobetasol Propionate Clobetasol Propionate(RX) , Clobetasol Propionate(RX) , Clobetasol Propionate(RX) , Temovate E(RX)
Clindamycin Phosphate , Benzoyl Peroxide Neuac(RX) , Clindamycin Phosphate And Benzoyl Peroxide(RX) , Clindamycin - Benzoyl Peroxide(RX) , Clindamycin Phosphate And Benzoyl Peroxide(RX) , Duac(RX)

Dosages

Route Formulation Per Unit Dose
Dental Injection
Intravenous Injectable
Topical Emulsion, Aerosol Foam 0.95%
Topical Emulsion, Cream 5%
Topical Lotion 1%W/W
Transdermal Film, Controlled Release 564MG

More Information

Usage Over Time

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