GLUTATHIONE

Molecular Excipient

Mwt. LogP HBD HBA PSA RB CSP3
307.0 -2.2 6 6 159.0 9 0.6
CAS
70188
UNII
GAN16C9B8O
SYNONYMS
ZINC ID(s)
Availability
Present in 86 ZINC catalogs

Known Active Genes

This compound has been observed to have activity at 10μM or less against the following gene(s).
Name Description Classification
GSTK1 Glutathione S-transferase kappa 1 Enzyme / Enzyme-Other

Clinical Trials

This compound has been an intervention in the following clincial trials (per clinicaltrials.gov).
Code Date Title Phase Status
NCT00002340 A Comparison of Atovaquone and Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia in HIV-Infected Patients Who Cannot Take TMP/SMX Phase 3 Completed
NCT00001996 A Phase II Open Randomized Comparison of 566C80 and Pentamidine Isethionate for the Treatment of Pneumocystis Carinii Pneumonia in AIDS Patients Who Are Intolerant of Trimethoprim / Sulfamethoxazole Phase 2 Completed
NCT02324426 2015-01-01 CNS Uptake of Intranasal Glutathione Phase 1 Recruiting
NCT02255461 2014-10-01 Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors Phase 1 Recruiting
NCT02251041 2014-09-01 Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers (CAPITL) Phase 2 Recruiting
NCT02154490 2014-06-01 Lung-MAP: S1400 Biomarker-Targeted Second-Line Therapy in Treating Patients With Recurrent Stage IIIB-IV Squamous Cell Lung Cancer Phase 2/Phase 3 Recruiting
NCT02125045 2014-02-01 Sublingual L-GSH Supplementation in Male Subjects With Smoking Habit and/or Hypertension Phase 3 Completed
NCT02041273 2014-01-01 Relative Bioavailability Of Palbociclib (PD-0332991) Under Fed And Fasted Conditions Phase 1 Completed
NCT01886443 2013-08-01 Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers Phase 1 Completed
NCT02399982 2013-02-01 Smartphone Technology and CBT-GSH in Binge Eaters Phase 1 Recruiting
NCT01398748 2012-07-01 Intranasal Glutathione in Parkinson's Disease Phase 1 Completed
NCT01450267 2010-06-01 Inhaled Glutathione (GSH) Versus Placebo in Cystic Fibrosis Phase 3 Recruiting
NCT02311907 2009-12-01 Glutathione in Preventing Peripheral Neuropathy Caused by Paclitaxel and Carboplatin in Patients With Ovarian Cancer, Fallopian Tube Cancer, and/or Primary Peritoneal Cancer Phase 3 Completed
NCT00979082 2009-12-01 Glutathione in Preventing Peripheral Neuropathy Caused by Paclitaxel and Carboplatin in Patients With Ovarian Cancer, Fallopian Tube Cancer, and/or Primary Peritoneal Cancer Phase 3 Active, Not Recruiting
NCT01016080 2009-02-01 Role of Oral Glutathione in Skin Whitening Phase 1 Completed
NCT00506688 2007-07-01 Efficacy and Safety Study of Inhaled Glutathione in Cystic Fibrosis Patients Phase 2 Completed
NCT00499122 2007-05-01 Oxidized Glutathione (NOV-002), Doxorubicin, Cyclophosphamide, and Docetaxel in Treating Women With Newly Diagnosed Stage IIB, or Stage IIIC Breast Cancer Phase 2 Completed
NCT00323583 2006-05-01 Weekly Dosing of an Integrative Chemotherapy Combination to Treat Advanced Pancreatic Cancer Phase 2 Recruiting
NCT00266331 2004-10-01 RayGel-An Alternative for Skin Care During External Beam Radiation Phase 2 Completed
NCT01177319 2003-09-01 Glutathione (GSH) In The Treatment of Parkinson's Disease Phase 2 Completed
NCT00910442 2002-02-01 Glutathione and Its Precursors in HIV-Infected Patients Phase 2 Completed
NCT00000974 1996-09-01 A Study of Two Forms of Pentamidine in HIV-Infected Children Who May Have Pneumocystis Carinii Pneumonia Phase 1 Completed
NCT00001027 1996-09-01 A Study of Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia (PCP) in HIV-Infected Children Who Cannot Take Trimethoprim-Sulfamethoxazole Phase 1 Completed
NCT00001028 1994-06-01 A Study of Pentamidine Plus Dapsone in the Prevention of Pneumocystis Carinii Pneumonia (PCP) in HIV-Infected Patients Who Cannot Take Trimethoprim or Sulfonamides Phase 3 Completed
NCT00000991 1994-04-01 A Study of Three Drugs Plus Zidovudine in the Prevention of Infections in HIV-Infected Patients Phase 3 Completed
NCT00000715 1991-09-01 A Controlled Trial Comparing the Efficacy of Aerosolized Pentamidine and Parenteral/Oral Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia in AIDS Phase 3 Completed
NCT00001013 1991-09-01 Comparison of Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Phase 3 Completed
NCT00000727 1991-08-01 A Controlled Comparative Trial of Sulfamethoxazole-Trimethoprim Versus Aerosolized Pentamidine for Secondary Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients Receiving Azidothymidine (AZT) Phase 3 Completed
NCT00000730 1989-03-01 Comparison of Three Treatments for Pneumocystis Pneumonia in AIDS Patients Phase 3 Terminated

(Browse) Purchasable Analogs in ZINC

Dosages

Route Formulation Per Unit Dose
Intramuscular Injection, Sustained Action 0.5%

More Information

Usage Over Time

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