LACTITOL MONOHYDRATE
Molecular Excipient
| Mwt. | LogP | HBD | HBA | PSA | RB | CSP3 |
|---|---|---|---|---|---|---|
| 342.0 | -5.4 | 8 | 11 | 190.0 | 5 | 1.0 |
- CAS
- 81025049
- UNII
- UH2K6W1Y64
- SYNONYMS
-
- ZINC ID(s)
- Availability
- Present in 32 ZINC catalogs
Known Active Genes
There has not been any activity reported at 10μM or less for this excipient (per ChEBML)
Clinical Trials
This compound has been an intervention in the following clincial trials (per clinicaltrials.gov).
| Code | Date | Title | Phase | Status |
|---|---|---|---|---|
| NCT02334163 | 2014-12-01 | The Effects of Nitazoxanide in Hepatic Encephalopathy | Phase 2 | Recruiting |
| NCT02228616 | 2014-10-01 | Efficacy and Safety of Prucalopride in Combination With Polyethylene Glycol or Lactulose in Women With Chronic Constipation | Phase 4 | Recruiting |
| NCT02307383 | 2014-10-01 | Pilot Study of the Effectiveness of Probiotics and Lactitol for the Decolonization of OXA-48 (Carbapenemase) Producing Klebsiella Pneumoniae Among Rectal Carriers | Phase 2 | Recruiting |
| NCT02158182 | 2014-07-01 | Lactulose, L-ornithine L-aspartate, or Rifaximin Versus Placebo for Preventing Hepatic Encephalopathy in Variceal Bleeding | Phase 4 | Recruiting |
| NCT02123017 | 2014-04-01 | Efficacy and Safety of Bisacodyl and Lactulose as a Preparation for Colonoscopy | Phase 2 | Completed |
| NCT01842113 | 2013-04-01 | Quality of Life and Nutritional Improvements in Cirrhotic Patients | Phase 4 | Terminated |
| NCT01756040 | 2013-02-01 | Intestinal Permeability in Preterm Infants | Phase 1 | Active, Not Recruiting |
| NCT01842581 | 2013-01-01 | The Safety/Efficacy Of Rifaximin With/Without Lactulose In Subjects With A History Of Recurrent Hepatic Encephalopathy | Phase 4 | Completed |
| NCT01650870 | 2012-07-01 | Safety, Efficacy, and Patient Preference of Split-Dose Crystalline Lactulose as a Preparation for Colonoscopy in Adults | Phase 2 | Completed |
| NCT02017119 | 2011-01-01 | Comparison Between Lactulose and Lactulose-Paraffin in Cirrhotic Patients | Phase 2 | Completed |
| NCT01256541 | 2010-12-01 | Kristalose as Bowel Evacuant Prior to Colonoscopy | Phase 1 | Completed |
| NCT02086825 | 2010-10-01 | A Randomized Comparison of Rifaximin Versus Lactulose in Hospitalized Cirrhotic Patients With Renal Failure | Phase 3 | Recruiting |
| NCT01008293 | 2009-10-01 | Effect of Probiotics in Treatment of Minimal Hepatic Encephalopathy (MHE) and Health Related Quality of Life | Phase 2/Phase 3 | Completed |
| NCT00712543 | 2009-06-01 | A Preference Study Comparing Kristalose® and Liquid Lactulose | Phase 4 | Completed |
| NCT00956150 | 2009-04-01 | Bacterial Overgrowth Associated With Chronic Multisymptom Illness Complex | Phase 1 | Recruiting |
| NCT00811434 | 2009-01-01 | Study of Lactulose in Children With Chronic Liver Disease | Phase 2 | Terminated |
| NCT00740142 | 2008-09-01 | Efficacy of Combined Oral L-Ornithine-L-Aspartate and Lactulose in Patients With Hepatic Encephalopathy | Phase 4 | Recruiting |
| NCT01178372 | 2008-09-01 | Secondary Prophylaxis of Hepatic Encephalopathy in Cirrhosis | Phase 4 | Recruiting |
| NCT00748904 | 2008-06-01 | Rifaximin Versus Lactulose in Renal Failure | Phase 4 | Recruiting |
| NCT00508482 | 2008-04-01 | A Clinical Standardization Study of the Preferred Acupuncture Treatment Protocol to Treat Functional Constipation | Phase 2 | Completed |
| NCT01175538 | 2008-01-01 | Primary Prophylaxis of Hepatic Encephalopathy in Patients With Cirrhosis | Phase 4 | Recruiting |
| NCT00553423 | 2007-11-01 | Lactulose for the Prevention of Hepatic Encephalopathy in Cirrhotic Patients With Upper Gastrointestinal Hemorrhage | Phase 3 | Recruiting |
| NCT00558038 | 2007-09-01 | Safety and Efficacy of AST-120 Compared to Lactulose in Patients With Hepatic Encephalopathy | Phase 2 | Completed |
| NCT00364689 | 2006-08-01 | RICE Trial: Rifaximin In Chronic Hepatic Encephalopathy - A Randomized, Controlled Trial | Phase 3 | Recruiting |
| NCT00255372 | 2005-04-01 | To Determine the Effect of Forlax® Treatment in Children With Chronic Constipation Who May Also Suffer From Soiling/ Faecal Incontinence. | Phase 3 | Completed |
| NCT00616876 | 2005-02-01 | Lactulose Supplementation in Premature Infants | Phase 2 | Completed |
| NCT00375375 | 2004-01-01 | Effect of Lactulose on Minimal Hepatic Encephalopathy and Health-Related Quality of Life | Phase 4 | Completed |
| NCT00160264 | 2003-01-01 | Study to Investigate if Adding Lactulose to Vitamin D and Calcium Has an Effect on the Preservation of Bone in Postmenopausal Women | Phase 4 | Completed |
| NCT00160290 | 2002-03-01 | Trial to Evaluate Effect of Lactulose on Hard Stools in Patients With Hemorrhoids or Anal Fissures | Phase 4 | Terminated |
| NCT00404040 | 2000-10-01 | Movicol in Childhood Constipation (ProMotion Study) | Phase 2 | Completed |
| NCT00403858 | 2000-10-01 | Movicol in Childhood Constipation (ProMotion Study) | Phase 2 | Completed |
| NCT00004796 | 1994-11-01 | Phase II Study of Lactulose and Circadian Rhythms in Patients With Cirrhosis | Phase 2 | Completed |