NONOXYNOL-9

Molecular Excipient

Mwt. LogP HBD HBA PSA RB CSP3
617.0 4.5 1 10 103.0 35 0.82
UNII
48Q180SH9T
CAS
26027-38-3
SYNONYMS
  • Nonoxynol-9
  • Tergitol Np-9
  • Nonoxynol 9
  • Polyethylene Glycol Mono(p-Nonylphenyl) Ether
  • Nonoxinol 9
  • Igepal Co-630
  • Peg-9 Nonyl Phenyl Ether
  • Norfox Np-9
  • Nonoxynol-9.5
  • Delfen
  • Today
  • Nonoxinol 9 [ep]
  • Nonoxynol 9 [usp]
  • Nonoxynol-9 [orange Book]
  • Nonoxinol 9 [mart.]
  • Nonoxynol-9 [inci]
  • Nonoxynol-9 [ii]
  • Nonoxynol 9 [usan]
  • Nonoxynol-9 [vandf]
  • Polyethylene Glycol 450 Nonyl Phenyl Ether
  • Nonylphenol Octa(oxyethylene) Ethanol
  • Nonaethylene Glycol Mono(nonylphenyl) Ether
  • Nonaethylene Glycol Nonylphenyl Ether
  • Polyoxyethylene(9)nonylphenyl Ether
  • Nonoxinol 9 [who-Dd]
  • Nonoxinol 9 [who-Ip]
  • Nonoxinolum 9 [who-Ip Latin]
ZINC ID(s)
Availability
Present in 26 ZINC catalogs

Known Active Genes

This compound has been observed to have activity at 10μM or less against the following gene(s).
Name Description Classification
SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter / Electrochemical-Transporter
SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter / Electrochemical-Transporter

Clinical Trials

This compound has been an intervention in the following clincial trials (per clinicaltrials.gov).
Code Date Title Phase Status
NCT02309554 2014-12-01 Postcoital Testing Study of the SILCS Diaphragm Used With 3% N-9 Gel, ContraGel, or No Gel Phase 1 Recruiting
NCT01593124 2012-05-01 Identification of Novel Biomarkers of Cervicovaginal Mucosal Inflammation Phase 2 Completed
NCT01232803 2010-10-01 Rectal Safety and Acceptability Study of Tenofovir 1% Gel Phase 1 Completed
NCT00389311 2007-04-01 A Pilot Study for Toxicity Evaluation of HIV Rectal Microbicides Phase 0 Completed
NCT00274261 2004-06-01 Study of the Safety and Contraceptive Efficacy of C31G Compared to Conceptrol® Phase 3 Completed
NCT00692952 2004-03-01 Effectiveness of BenZalkonium Chloride Gel as Vaginal Contraceptive: a Multicentric Randomized Controlled Trial Phase 2 Completed
NCT00000926 2001-02-01 A Study of Nonoxynol-9 (N-9) and HIV Infection Phase 3 Completed
NCT00000929 1999-07-01 A Study of the Effects of Advantage 24 on the Rectum Phase 1 Completed

(Browse) Purchasable Analogs in ZINC

Dosages

Route Formulation Per Unit Dose
Ophthalmic Solution 0.13%
Topical Solution 0.01%

More Information

Usage Over Time

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