Application Nr Approved Date Route Status External Links
ANDA077298 2010-04-15 Oral RX Google , Wikipedia , PubMed , DailyMed , Raw OpenFDA , ECHA , ToxNet , JECFA , FAO , 21 CFR

Indications and Purposes

1 Indications And Usage Metoprolol Succinate Is A Beta1-Selective Adrenoceptor Blocking Agent. Metoprolol Succinate Extended-Release Tablets Usp Are Indicated For The Treatment Of: Hypertension (1.1) Angina Pectoris (1.2) Heart Failure - For The Treatment Of Stable, Symptomatic (nyha Class Ii Or Iii) Heart Failure Of Ischemic, Hypertensive, Or Cardiomyopathic Origin.(1.3) 1.1 Hypertension Metoprolol Succinate Extended-Release Tablets Usp Are Indicated For The Treatment Of Hypertension. It May Be Used Alone Or In Combination With Other Antihypertensive Agents [see Dosage And Administration (2) ]. 1.2 Angina Pectoris Metoprolol Succinate Extended-Release Tablets Usp Are Indicated In The Long-Term Treatment Of Angina Pectoris, To Reduce Angina Attacks And To Improve Exercise Tolerance. 1.3 Heart Failure Metoprolol Succinate Extended-Release Tablets Usp Are Indicated For The Treatment Of Stable, Symptomatic (nyha Class Ii Or Iii) Heart Failure Of Ischemic, Hypertensive, Or Cardiomyopathic Origin. It Was Studied In Patients Already Receiving Ace Inhibitors, Diuretics, And, In The Majority Of Cases, Digitalis. In This Population, Metoprolol Succinate Extended-Release Tablets Decreased The Rate Of Mortality Plus Hospitalization, Largely Through A Reduction In Cardiovascular Mortality And Hospitalizations For Heart Failure.

All Formulated Excipients (9 Total)

Name Structure Kind Function Status
1. Starch, Corn STARCH, CORN Unresolved
2. Glyceryl Monostearate GLYCERYL MONOSTEARATE Molecular
3. Hypromelloses HYPROMELLOSES Unresolved
4. Methacrylic Acid Copolymer METHACRYLIC ACID COPOLYMER Unresolved
5. Cellulose, Microcrystalline CELLULOSE, MICROCRYSTALLINE Unresolved
6. Poloxamer 188 POLOXAMER 188 Unresolved
7. Polyethylene Glycols POLYETHYLENE GLYCOLS Unresolved
8. Polysorbate 80 POLYSORBATE 80 Unresolved AF-Antifoaming (or defoaming) agent , EMUL-Emulsifier , MISC-Miscellaneous , SDA-Solubilizing & dispersing agent REG-Food additives for which a petition has been filed and a regulation issued.
9. Sucrose SUCROSE Molecular NUTRS-Nutritive Sweetener GRAS-Generally recognized as safe.

Active Ingredients ( 1 Total)

Name Structure ZINC ID(s)
1. Metoprolol Succinate METOPROLOL SUCCINATE ZINC1530717

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