Korlym

Product manufactured by Corcept Therapeutics Inc

Application Nr Approved Date Route Status External Links
NDA202107 2012-02-17 Oral RX Google , Wikipedia , PubMed , DailyMed , Raw OpenFDA , ECHA , ToxNet , JECFA , FAO , 21 CFR

Indications and Purposes

1 Indications And Usage Korlym (mifepristone) Is A Cortisol Receptor Blocker Indicated To Control Hyperglycemia Secondary To Hypercortisolism In Adult Patients With Endogenous Cushing's Syndrome Who Have Type 2 Diabetes Mellitus Or Glucose Intolerance And Have Failed Surgery Or Are Not Candidates For Surgery. Limitations Of Use: Korlym Should Not Be Used In The Treatment Of Patients With Type 2 Diabetes Unless It Is Secondary To Cushing's Syndrome. Korlym (mifepristone) Is A Cortisol Receptor Blocker Indicated To Control Hyperglycemia Secondary To Hypercortisolism In Adult Patients With Endogenous Cushing's Syndrome Who Have Type 2 Diabetes Mellitus Or Glucose Intolerance And Have Failed Surgery Or Are Not Candidates For Surgery. Important Limitations Of Use: Do Not Use For The Treatment Of Type 2 Diabetes Mellitus Unrelated To Endogenous Cushing's Syndrome.

All Formulated Excipients (6 Total)

Name Structure Kind Function Status
1. Sodium Lauryl Sulfate SODIUM LAURYL SULFATE Molecular AF-Antifoaming (or defoaming) agent , CTG-Component or coating , EMUL-Emulsifier , SANI-Sanitizing agent , SDA-Solubilizing & dispersing agent REG-Food additives for which a petition has been filed and a regulation issued.
2. Magnesium Stearate MAGNESIUM STEARATE Molecular AF-Antifoaming (or defoaming) agent , MISC-Miscellaneous REG-Food additives for which a petition has been filed and a regulation issued.
3. Hypromelloses HYPROMELLOSES Unresolved
4. Titanium Dioxide TITANIUM DIOXIDE Unresolved DYE-Dye
5. Triacetin TRIACETIN Molecular MISC-Miscellaneous GRAS-Generally recognized as safe.
6. Polysorbate 80 POLYSORBATE 80 Unresolved AF-Antifoaming (or defoaming) agent , EMUL-Emulsifier , MISC-Miscellaneous , SDA-Solubilizing & dispersing agent REG-Food additives for which a petition has been filed and a regulation issued.

Active Ingredients ( 1 Total)

Name Structure ZINC ID(s)
1. Mifepristone

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