GLUCURONIC ACID

Molecular Excipient

Mwt. LogP HBD HBA PSA RB CSP3
193.0 -4.5 4 7 130.0 1 0.83
CAS
6556123
UNII
8A5D83Q4RW
SYNONYMS
ZINC ID(s)
Availability
Present in 30 ZINC catalogs

Known Active Genes

There has not been any activity reported at 10μM or less for this excipient (per ChEBML)

Clinical Trials

This compound has been an intervention in the following clincial trials (per clinicaltrials.gov).
Code Date Title Phase Status
NCT00002120 Randomized Phase I Study of Trimetrexate Glucuronate (TMTX) With Leucovorin (LCV) Protection Plus Dapsone Versus Trimethoprim / Sulfamethoxazole (TMP/SMX) for Treatment of Moderately Severe Episodes of Pneumocystis Carinii Pneumonia Phase 1 Completed
NCT00001016 2007-08-01 A Treatment Protocol for the Use of Trimetrexate With Leucovorin Rescue for AIDS Patients With Pneumocystis Carinii Pneumonia and Serious Intolerance to Approved Therapies Phase 3 Completed
NCT00119301 2005-04-01 Methotrexate, Trimetrexate Glucuronate, and Leucovorin in Treating Patients With Refractory or Recurrent Osteosarcoma Phase 1 Completed
NCT00000714 2004-07-01 An Open, Prospective, Multicenter Study of Trimetrexate With Leucovorin Rescue for AIDS Patients With Pneumocystis Carinii Pneumonia (PCP) and Serious Intolerance to Approved Therapies Phase 3 Completed
NCT00000724 2004-07-01 A Study of Trimetrexate With Leucovorin Rescue for AIDS Patients Who Are Refractory to Standard Therapies for Pneumocystis Carinii Pneumonia Phase 3 Completed
NCT00003776 1998-12-01 Combination Chemotherapy and Surgery in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma Phase 2 Completed
NCT00003446 1997-12-01 Chemotherapy in Treating Patients With Recurrent or Metastatic Colorectal Cancer Phase 2 Completed
NCT00002738 1996-01-01 Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia, Osteosarcoma, or Non-Hodgkin's Lymphoma Phase 2 Completed
NCT00002955 1995-08-01 Combination Chemotherapy in Treating Patients With Advanced Cancer of the Pancreas Phase 2 Completed
NCT00001013 1991-09-01 Comparison of Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Phase 3 Completed
NCT00001014 1991-09-01 Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Phase 3 Completed
NCT00000998 1989-04-01 A Study of Trimetrexate in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Not Previously Treated for PCP Phase 1 Completed
NCT00000730 1989-03-01 Comparison of Three Treatments for Pneumocystis Pneumonia in AIDS Patients Phase 3 Terminated

(Browse) Purchasable Analogs in ZINC

Dosages

Route Formulation Per Unit Dose
Intravenous Injection

More Information

Usage Over Time

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