GLUCURONIC ACID
Molecular Excipient
| Mwt. | LogP | HBD | HBA | PSA | RB | CSP3 |
|---|---|---|---|---|---|---|
| 193.0 | -4.5 | 4 | 7 | 130.0 | 1 | 0.83 |
- CAS
- 6556123
- UNII
- 8A5D83Q4RW
- SYNONYMS
-
- ZINC ID(s)
- Availability
- Present in 30 ZINC catalogs
Known Active Genes
There has not been any activity reported at 10μM or less for this excipient (per ChEBML)
Clinical Trials
This compound has been an intervention in the following clincial trials (per clinicaltrials.gov).
| Code | Date | Title | Phase | Status |
|---|---|---|---|---|
| NCT00002120 | Randomized Phase I Study of Trimetrexate Glucuronate (TMTX) With Leucovorin (LCV) Protection Plus Dapsone Versus Trimethoprim / Sulfamethoxazole (TMP/SMX) for Treatment of Moderately Severe Episodes of Pneumocystis Carinii Pneumonia | Phase 1 | Completed | |
| NCT00001016 | 2007-08-01 | A Treatment Protocol for the Use of Trimetrexate With Leucovorin Rescue for AIDS Patients With Pneumocystis Carinii Pneumonia and Serious Intolerance to Approved Therapies | Phase 3 | Completed |
| NCT00119301 | 2005-04-01 | Methotrexate, Trimetrexate Glucuronate, and Leucovorin in Treating Patients With Refractory or Recurrent Osteosarcoma | Phase 1 | Completed |
| NCT00000714 | 2004-07-01 | An Open, Prospective, Multicenter Study of Trimetrexate With Leucovorin Rescue for AIDS Patients With Pneumocystis Carinii Pneumonia (PCP) and Serious Intolerance to Approved Therapies | Phase 3 | Completed |
| NCT00000724 | 2004-07-01 | A Study of Trimetrexate With Leucovorin Rescue for AIDS Patients Who Are Refractory to Standard Therapies for Pneumocystis Carinii Pneumonia | Phase 3 | Completed |
| NCT00003776 | 1998-12-01 | Combination Chemotherapy and Surgery in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma | Phase 2 | Completed |
| NCT00003446 | 1997-12-01 | Chemotherapy in Treating Patients With Recurrent or Metastatic Colorectal Cancer | Phase 2 | Completed |
| NCT00002738 | 1996-01-01 | Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia, Osteosarcoma, or Non-Hodgkin's Lymphoma | Phase 2 | Completed |
| NCT00002955 | 1995-08-01 | Combination Chemotherapy in Treating Patients With Advanced Cancer of the Pancreas | Phase 2 | Completed |
| NCT00001013 | 1991-09-01 | Comparison of Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS | Phase 3 | Completed |
| NCT00001014 | 1991-09-01 | Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS | Phase 3 | Completed |
| NCT00000998 | 1989-04-01 | A Study of Trimetrexate in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Not Previously Treated for PCP | Phase 1 | Completed |
| NCT00000730 | 1989-03-01 | Comparison of Three Treatments for Pneumocystis Pneumonia in AIDS Patients | Phase 3 | Terminated |