GLUTAMIC ACID, DL-
Molecular Excipient
| Mwt. | LogP | HBD | HBA | PSA | RB | CSP3 |
|---|---|---|---|---|---|---|
| 146.0 | -4.1 | 1 | 4 | 108.0 | 4 | 0.6 |
- CAS
- 617652
- UNII
- 61LJO5I15S
- SYNONYMS
-
- ZINC ID(s)
- Availability
- Present in 95 ZINC catalogs
Known Active Genes
This compound has been observed to have activity at 10μM or less against the following gene(s).
| Name | Description | Classification |
|---|---|---|
| MURI | Glutamate racemase | Enzyme / Enzyme-Other |
| GRIK2 | Ionotropic glutamate receptor subunit GluR6(Q) | Ion Channel / Lgic |
| GRIA2 | Glutamate receptor 2 | Ion Channel / Lgic |
| GRIK5 | Glutamate receptor ionotropic, kainate 5 | Ion Channel / Lgic |
| GRIK1 | Glutamate receptor ionotropic, kainate 1 | Ion Channel / Lgic |
| GRIK3 | Glutamate receptor ionotropic, kainate 3 | Ion Channel / Lgic |
| GRIA4 | Glutamate receptor 4 | Ion Channel / Lgic |
| GRIA1 | Glutamate receptor 1 | Ion Channel / Lgic |
| GRM1 | Metabotropic glutamate receptor 1 | Membrane Receptor / Gpcr-C |
| GRM3 | Metabotropic glutamate receptor 3 | Membrane Receptor / Gpcr-C |
| GRM8 | Metabotropic glutamate receptor 8 | Membrane Receptor / Gpcr-C |
| GRM2 | Metabotropic glutamate receptor 2 | Membrane Receptor / Gpcr-C |
| GRM4 | Metabotropic glutamate receptor 4 | Membrane Receptor / Gpcr-C |
| GRM5 | Metabotropic glutamate receptor 5 | Membrane Receptor / Gpcr-C |
| GRM6 | Metabotropic glutamate receptor 6 | Membrane Receptor / Gpcr-C |
Clinical Trials
This compound has been an intervention in the following clincial trials (per clinicaltrials.gov).
| Code | Date | Title | Phase | Status |
|---|---|---|---|---|
| NCT02002130 | 2015-01-01 | The Use of Glutamic Acid Decarboxylase (GAD) and Gamma-Amino Butyric Acid (GABA) in the Treatment of Type I Diabetes | Phase 1 | Not Yet Recruiting |
| NCT01826045 | 2013-03-01 | Efficacy and Safety Study of PGA (Poly-gamma Glutamic Acid) for Cervical Intraepithelial Neoplasia | Phase 2 | Recruiting |
| NCT01501942 | 2012-02-01 | Efficacy, Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of Oral Administration of AIM-102 in Patients With Mild to Moderate Allergic Asthma | Phase 2 | Completed |
| NCT00369564 | 2007-05-01 | Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer | Phase 3 | Completed |
| NCT00300040 | 2006-05-01 | Safety/Feasibility Study of HBOC-201 in Amputation at/Below Knee From Critical Lower Limb Ischemia | Phase 2 | Terminated |
| NCT00301535 | 2006-02-01 | A Study of Hemopure® to Enhance Tissue Preservation During Cardiopulmonary Bypass Surgery | Phase 2 | Recruiting |
| NCT00489827 | 2005-10-01 | Glutamate for Metabolic Intervention in Coronary Surgery | Phase 3 | Active, Not Recruiting |
| NCT00213915 | 2004-02-01 | L-Arginine Supplementation and Exercise; L-Arginine Supplementation and Renal Function | Phase 4 | Completed |
| NCT00069901 | 2003-02-01 | Phase II CT-2103/Carboplatin in Ovarian Cancer | Phase 2 | Completed |
| NCT00357019 | 2001-04-01 | Study of the Clinical and Biological Efficacity of NAAXIA SINE® in Vernal Keratoconjunctivitis | Phase 4 | Completed |
| NCT00000768 | 1998-08-01 | A Randomized Comparative Pharmacokinetic Study of Oral Ganciclovir After Treatment With Intravenous Ganciclovir for Cytomegalovirus Gastrointestinal Disease in AIDS Patients | Phase 1 | Completed |