HYALURONATE SODIUM
Molecular Excipient
| Mwt. | LogP | HBD | HBA | PSA | RB | CSP3 |
|---|---|---|---|---|---|---|
| 381.0 | -4.1 | 7 | 10 | 195.0 | 5 | 0.86 |
- CAS
- 9067327
- UNII
- YSE9PPT4TH
- SYNONYMS
-
- ZINC ID(s)
- Availability
- Present in 11 ZINC catalogs
Known Active Genes
There has not been any activity reported at 10μM or less for this excipient (per ChEBML)
Clinical Trials
This compound has been an intervention in the following clincial trials (per clinicaltrials.gov).
| Code | Date | Title | Phase | Status |
|---|---|---|---|---|
| NCT00493662 | Cross-Over Evaluation of Two Lubricating Eye Drops | Phase 4 | Completed | |
| NCT01442571 | Hyaluronic Acid Injection Post Arthroscopy - Does it Improve Immediate Function? Double Blind Controlled Prospective Study | Phase 1/Phase 2 | Not Yet Recruiting | |
| NCT02034890 | 2015-07-01 | Intravesical Instillation of Hyaluronic Acid to Decrease Incidence of Urinary Tract Infection | Phase 4 | Not Yet Recruiting |
| NCT02368561 | 2015-03-01 | Treatment of Insertional Achilles Tendinopathy by Hyaluronic Acid Injection | Phase 0 | Not Yet Recruiting |
| NCT02323451 | 2014-12-01 | Medical Chitosan or Sodium Hyaluronate for Knee Osteoarthritis (CHOOSE) | Phase 4 | Recruiting |
| NCT02257957 | 2014-11-01 | Platelet -Rich Plasma (PRP) Injection for the Treatment of Severe Dry Eye | Phase 3 | Not Yet Recruiting |
| NCT02265575 | 2014-10-01 | Hylenex-Assisted Resuscitation in Kenya (HARK) Trial for the Management of Dehydration | Phase 2 | Not Yet Recruiting |
| NCT02211521 | 2014-08-01 | Comparison of Autologous Platelet-rich Plasma With Hyaluronic Acid for the Treatment of Osteoarthritis of the Knee Joint | Phase 3 | Recruiting |
| NCT02122601 | 2014-04-01 | An Open-label, Single Arm, Multi-center, Phase 3 Study to Evaluate the Safety and Efficacy of Retreatment With Intra-articular LBSA0103 Injections in the Patients With Osteoarthritis of the Knee | Phase 3 | Recruiting |
| NCT02117687 | 2014-04-01 | A Safety and Efficacy Study of OPTIVE FUSION™ With VISMED® Multi for the Management of Dry Eye | Phase 4 | Active, Not Recruiting |
| NCT02127723 | 2014-04-01 | (Macrolane VR30) in Buttocks Reshaping and contouringCellulite (Macrolane VR30) in Buttocks Reshaping and Contouring | Phase 4 | Active, Not Recruiting |
| NCT02039804 | 2014-03-01 | Sodium Hyaluronate Injection and Corticosteroids in Trochanteric Bursitis: a Randomized Controlled Study. | Phase 3 | Not Yet Recruiting |
| NCT02188771 | 2014-02-01 | A Phase I, Prospective, Randomized, Open-label, Active-Controlled Clinical Trial for Safety Evaluation of Intra-articular Injection of RegenoGel-SP for the Treatment of Moderate to Severe Osteoarthritis | Phase 1/Phase 2 | Recruiting |
| NCT02162693 | 2013-10-01 | Clinical Trial of Autologous Adipose Tissue-Derived Mesenchymal Progenitor Cells (MPCs) Therapy for Knee Osteoarthritis | Phase 2 | Active, Not Recruiting |
| NCT02091674 | 2013-08-01 | Management of Acute Ankle Sprain With Sodium Hyaluronate | Phase 2 | Completed |
| NCT01935531 | 2013-06-01 | Effects of Topical Diclofenac on Tumor Metabolism | Phase 4 | Active, Not Recruiting |
| NCT01948583 | 2013-05-01 | Humectant Activity of a New Formulation of Gynomunal® Vaginalgel | Phase 4 | Completed |
| NCT02014428 | 2013-04-01 | Oral Low-molecular Weight Hyaluronic Acid in the Treatment of Atrophic Vaginitis | Phase 4 | Completed |
| NCT01811654 | 2013-04-01 | Effectiveness Trial for Evaluating IAHA for PFPS | Phase 4 | Recruiting |
| NCT01838252 | 2013-02-01 | Hyaluronic Acid Gels for Lower Lid Retraction | Phase 4 | Withdrawn |
| NCT01738243 | 2012-12-01 | Hyaluronic Acid Gels for Upper Lid Retraction in Active Stage Thyroid Eye Disease | Phase 4 | Recruiting |
| NCT02063373 | 2012-09-01 | Gait, Stair Climbing and Postural Stability in Knee Osteoarthritis Patients After Hyaluronic Acid Injection | Phase 3 | Completed |
| NCT02123368 | 2012-05-01 | Treatment of Knee Osteoarthritis by Intra-articular Injection of Bone Marrow Mesenchymal Stem Cells | Phase 1/Phase 2 | Active, Not Recruiting |
| NCT01586312 | 2012-04-01 | Treatment of Knee Osteoarthritis With Allogenic Mesenchymal Stem Cells | Phase 1/Phase 2 | Completed |
| NCT01543737 | 2012-02-01 | Effectiveness of Two Hyaluronic Acids in Osteoarthritis of the Knee | Phase 4 | Suspended |
| NCT01545557 | 2012-02-01 | Pan Facial Volume Restoration | Phase 4 | Completed |
| NCT01735058 | 2012-02-01 | Ultrasonography Guided Subacromial Sodium Hyaluronate Injection in Rotator Cuff Disease | Phase 2/Phase 3 | Recruiting |
| NCT01524913 | 2012-01-01 | A Double Blind Study Comparing Hyaluronic Acid, Corticosteroid and Placebo During Arthrocentesis for TMJ | Phase 4 | Active, Not Recruiting |
| NCT00958425 | 2012-01-01 | Intraoperative Hyaluronic Acid Gel Injection for Improvement of Scar Quality Following Reduction Mammaplasty | Phase 3 | Not Yet Recruiting |
| NCT01493180 | 2011-12-01 | Exploratory Study of OPC-12759 Ophthalmic Suspension | Phase 2 | Completed |
| NCT01588925 | 2011-11-01 | Hearing Preservation Using Dexamethasone and Hyaluronic Acid for Cochlear Implantation | Phase 2 | Completed |
| NCT02207608 | 2011-09-01 | Influence of Hyaluronic Acid on Bacillus Calmette-Guérin Local Side Effects | Phase 2 | Completed |
| NCT01270412 | 2011-09-01 | Platelet Rich Plasma (PRP) as a Treatment for Knee Osteoarthritis PRP as a Treatment for Knee Osteoarthritis | Phase 2/Phase 3 | Not Yet Recruiting |
| NCT02039531 | 2011-08-01 | Effect Of Plasma Rich In Growth Factors In Knee Osteoarthritis | Phase 3 | Active, Not Recruiting |
| NCT01290367 | 2011-08-01 | Safety and Preliminary Efficacy Study of Mesenchymal Precursor Cells (MPCs) in Subjects With Lumbar Back Pain | Phase 2 | Active, Not Recruiting |
| NCT01382225 | 2011-07-01 | Sodium Hyaluronate Ophthalmic Solution, 0.18% for Treatment of Dry Eye Syndrome | Phase 3 | Completed |
| NCT01459640 | 2011-03-01 | Intra-Articular Autologous Bone Marrow Mesenchymal Stem Cells Transplantation to Treat Mild to Moderate Osteoarthritis | Phase 2 | Recruiting |
| NCT01305187 | 2011-02-01 | Non-inferiority of Belotero® Basic Versus Juvéderm® Ultra 3 | Phase 4 | Completed |
| NCT01295580 | 2011-01-01 | Comparative Study of Safety and Efficacy of Two Hyaluronic Acids for the Treatment of Knee Osteoarthritis | Phase 3 | Completed |
| NCT01290497 | 2010-11-01 | Efficacy and Safety of 3 Different Dosage Regimens of Hyaluronic Acid in Patients With Knee Osteoarthritis (OA) | Phase 4 | Completed |
| NCT00993707 | 2010-11-01 | Safety Study of CTX-100 Inhalation Solution (Formerly ETX-100) | Phase 2 | Recruiting |
| NCT02165020 | 2010-11-01 | Hyaluronic Acid for Hypofractionated Prostate Radiotherapy | Phase 2 | Active, Not Recruiting |
| NCT01135511 | 2010-07-01 | A Phase II, Dose Ranging Study Of CP-690,550 Eye Drops In Patients With Dry Eye Disease | Phase 2 | Completed |
| NCT01787630 | 2010-01-01 | To Evaluate the Technique and Effects of Separating the Prostate and Rectum With Hyaluronic Acid During Radiotherapy | Phase 2/Phase 3 | Recruiting |
| NCT00987727 | 2009-11-01 | Safety and Efficacy of Carboxymethylcellulose for Ocular Surface Integrity in Symptomatic Dry Eye | Phase 4 | Completed |
| NCT01076673 | 2009-10-01 | Effect of Autologous Peripheral Blood Stem Cell Treatment on Articular Cartilage Regeneration | Phase 2 | Completed |
| NCT00988091 | 2009-09-01 | Investigation of 1.2% Sodium Hyaluronate for Treatment of Painful Chronic Osteoarthritis of the Knee | Phase 3 | Completed |
| NCT01066026 | 2009-07-01 | Comparison of Safety and Efficacy of a Metallic Cannula Versus a Standard Needle to Inject Hyaluronic Acid for Nasolabial Fold | Phase 2 | Completed |
| NCT01387620 | 2009-06-01 | Comparison of DisCoVisc and Hydroxypropylmethylcellulose 2% | Phase 4 | Completed |
| NCT00938704 | 2009-06-01 | Study to Compare the Efficacy and Safety of Two Non-Preserved Artificial Tears for the Treatment of Dry Eye Signs and Symptoms | Phase 4 | Completed |
| NCT01670578 | 2009-02-01 | Platelet-rich Plasma vs Viscosupplementation in the Treatment of Knee Articular Degenerative Pathology | Phase 4 | Completed |
| NCT01267214 | 2009-02-01 | The Efficacy and Safety of Intraarticular Sodium Hyaluronate (Hyalgan) After Proximal Tibial Osteotomy in Treatment of Knee Osteoarthritis Patients | Phase 2 | Completed |
| NCT00809198 | 2008-12-01 | Kynex Versus Refresh Plus Study in Subject With Dry Eye | Phase 4 | Completed |
| NCT00850889 | 2008-11-01 | Juvederm Ultra With Lidocaine Compared With Restylane for the Correction of Nasolabial Folds | Phase 4 | Completed |
| NCT01557868 | 2008-10-01 | Prediction of Response to Intra-articular Injections of Hyaluronic Acid for Knee Osteoarthritis | Phase 4 | Completed |
| NCT00760045 | 2008-08-01 | Clinical Pharmacological Study of AL-43546 Ophthalmic Product in Subjects With Shortened Tear Film Break Up Time | Phase 2 | Completed |
| NCT00750724 | 2008-07-01 | "Efficacy Study of ""Go On"" in Magnetic Resonance Imaging (MRI) Improvement in Osteoarthritis (OA) Knee" | Phase 3 | Completed |
| NCT00778076 | 2008-07-01 | The Impact of Hyaluronic Acid Injections on Osteoarthritic Knee Mechanics | Phase 4 | Active, Not Recruiting |
| NCT01240382 | 2008-02-01 | Phase III Confirmatory Study of DE-089 Ophthalmic Solution in Patients With Dry Eye | Phase 3 | Completed |
| NCT00607685 | 2008-02-01 | 5FU vs 5FU With Viscoelastic Formulation for the Prevention of Scarring Post-trabeculectomy | Phase 4 | Completed |
| NCT00782197 | 2008-01-01 | Autologous Plasma Rich in Growth Factors (PRGF) Treating the Symptomatic Knee OA | Phase 4 | Completed |
| NCT00728611 | 2008-01-01 | Preparation Rich in Growth Factors (PRGF) Treatment for Osteoarthritis of the Knee | Phase 2/Phase 3 | Completed |
| NCT00556608 | 2007-11-01 | Efficacy Study of Intra-articular Hyaluronic Acid in the Knee Osteoarthritis | Phase 4 | Completed |
| NCT00565643 | 2007-11-01 | Seprafilm® Adhesion Barrier and Cesarean Delivery | Phase 4 | Completed |
| NCT00918736 | 2007-10-01 | Efficacy of 3 Weekly Injections of Hyaluronate in Patients With Ankle Osteoarthritis | Phase 2 | Completed |
| NCT00761202 | 2007-08-01 | Performance and Acceptance of Optive Versus Hylocomod Eyedrops in Patients With Dry Eye Symptoms | Phase 4 | Completed |
| NCT00422643 | 2007-03-01 | The Effect of Intraaricular Knee Injections of Hyaluronic Acid (HA) on Bone and Cartilaginous Debris, as a Therapeutic Indicator | Phase 4 | Not Yet Recruiting |
| NCT00423371 | 2006-12-01 | Double-Blind,Randomized,Placebo-Controlled Efficacy & Safety Study of EUFLEXXA™ for Treatment of OA of the First CMC | Phase 2/Phase 3 | Completed |
| NCT00599716 | 2006-12-01 | Safety and Efficacy Assessment of Vismed® (Sodium Hyaluronate) for the Treatment of Dry Eye Syndrome | Phase 3 | Completed |
| NCT00830830 | 2005-12-01 | TREAD-20 Extension - Treatment of Knee Pain Due to Osteoarthritis | Phase 4 | Completed |
| NCT00429520 | 2005-12-01 | Hyaluronic Acid Filler IMD1 Basic for Correction of Nasolabial Folds | Phase 4 | Completed |
| NCT01239810 | 2005-06-01 | Intra-articular Hyaluronic Acid in Mild to Moderate Knee Osteoarthritis | Phase 2 | Completed |
| NCT00330135 | 2005-01-01 | The Efficacy Study of Sodium Hyaluronate to Treat Symptomatic Hip Osteoarthritis | Phase 3 | Terminated |
| NCT00130468 | 2004-11-01 | TREAD-20: Trial of Hyalgan Three Injection-Regimen for the Treatment of Knee Pain Due to Osteoarthritis | Phase 4 | Completed |
| NCT00669032 | 2003-10-01 | Efficacy and Safety of Repeated Intraarticular Injections of Hyaluronic Acid in Patients With OA of the Knee | Phase 4 | Completed |
| NCT00731289 | 2003-07-01 | Gait Patterns After Intraarticular Treatment of Patients With Osteoarthritis of the Knee | Phase 4 | Completed |
| NCT02337166 | 2002-12-01 | Regeneration of Human Intrabony Defects With rhFGF-2/HA | Phase 1/Phase 2 | Completed |
| NCT00377624 | 2002-01-01 | HUPS: Hyalgan Use in Painful Shoulder | Phase 3 | Completed |