METHYLENE BLUE

Molecular Excipient

Mwt. LogP HBD HBA PSA RB CSP3
284.0 2.5 0 3 19.0 1 0.25
CAS
7220793
UNII
T42P99266K
SYNONYMS
ZINC ID(s)
Availability
Present in 63 ZINC catalogs

Known Active Genes

This compound has been observed to have activity at 10μM or less against the following gene(s).
Name Description Classification
GR3 Glutathione reductase Enzyme / Enzyme-Other
MAPT Microtubule-associated protein tau Unclassified / Unclassified

Clinical Trials

This compound has been an intervention in the following clincial trials (per clinicaltrials.gov).
Code Date Title Phase Status
NCT02380573 2015-07-01 Cognitive and Functional Connectivity Effects of Methylene Blue in Healthy Aging and Mild Cognitive Impairment Phase 2 Not Yet Recruiting
NCT02240498 2014-09-01 Safety and Feasibility Study of Methylene Blue Photodynamic Therapy to Sterilize Deep Tissue Abscess Cavities Phase 1 Recruiting
NCT01694966 2013-09-01 The Safety and Efficacy of Methylene Blue MMX® Modified Release Tablets Administered to Subjects Undergoing Screening or Surveillance Colonoscopy Phase 3 Recruiting
NCT01836094 2013-08-01 Effects of USP Methylene Blue on Cognitive and fMRI Brain Activity Phase 2 Enrolling By Invitation
NCT01668433 2013-07-01 Pharmacokinetic and in Vitro Transmission Blocking Activities Study of Primaquine Compare to Methylene Blue in Healthy Volunteer Both G6PD Normal and G6PD Deficiency Phase 1 Recruiting
NCT01847612 2013-05-01 Use of Indocyanine Green Cholangiography and Methylene Blue to Detect Postoperative Biliary Fistula After Hepatectomy Phase 3 Recruiting
NCT01823172 2013-04-01 Second Echelon Node Study With Methylene Blue Phase 1 Completed
NCT01657448 2013-03-01 Efficacy Study of Acriflavine Hydrochloride + Methenamine + Methylthioninium Chloride vs Placebo for the Rapid Relief of Symptoms Urinary Tract Infection Phase 3 Not Yet Recruiting
NCT02295774 2013-02-01 Effect of Oral Administration of Methylene Blue MMX Tablets on Double Stranded DNA Phase 2 Recruiting
NCT01797978 2013-02-01 Methylene Blue in Severe Sepsis and Septic Shock Phase 3 Recruiting
NCT01407887 2011-08-01 Efficacy and Safety of Artesunate-amodiaquine-methylene for Malaria Treatment in Children Phase 2 Completed
NCT01386879 2011-07-01 Evaluation of Above the Cuff Suctioning During General Anesthesia Phase 4 Terminated
NCT01276054 2010-12-01 Sentinel and/or Axillary Lymph Node Biopsy With or Without Axillary Reverse Mapping in Reducing Incidence and Severity of Arm Lymphedema in Stage 0-2 Patients. Phase 2 Terminated
NCT01188694 2009-09-01 Enhancing Extinction Learning in Post Traumatic Stress Disorder (PTSD) Phase 2 Active, Not Recruiting
NCT00354380 2006-09-01 Safety and Efficacy of Methylene Blue Combined With Artesunate or Amodiaquine for Malaria Treatment in Children of Burkina Faso: a Pilot Study Phase 2 Completed
NCT00784849 2004-11-01 Feasibility of One-Step Sentinel Lymph Node (SLN) Biopsy With Radiolabeled Methylene Blue (IND 70,627) Phase 2 Completed
NCT00159510 2004-04-01 Studies of Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome Phase 1 Active, Not Recruiting
NCT00214877 2003-11-01 Methylene Blue for Cognitive Dysfunction in Bipolar Disorder Phase 3 Completed

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Dosages

Route Formulation Per Unit Dose
Intravenous Injection

More Information

Usage Over Time

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