TOCOPHEROL
Molecular Excipient
| Mwt. | LogP | HBD | HBA | PSA | RB | CSP3 |
|---|---|---|---|---|---|---|
| 417.0 | 8.5 | 1 | 2 | 29.0 | 12 | 0.79 |
- CAS
- 1406662
- UNII
- R0ZB2556P8
- SYNONYMS
-
- ZINC ID(s)
- Availability
- Present in 7 ZINC catalogs
Known Active Genes
There has not been any activity reported at 10μM or less for this excipient (per ChEBML)
Clinical Trials
This compound has been an intervention in the following clincial trials (per clinicaltrials.gov).
| Code | Date | Title | Phase | Status |
|---|---|---|---|---|
| NCT02368457 | 2015-02-01 | Management of Mandibular ORN: PENTO as Medical Treatment | Phase 4 | Recruiting |
| NCT02251041 | 2014-09-01 | Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers (CAPITL) | Phase 2 | Recruiting |
| NCT02104505 | 2014-07-01 | Effect of Gamma Tocopherol Enriched Supplementation on Response to Inhaled LPS | Phase 1/Phase 2 | Recruiting |
| NCT01886443 | 2013-08-01 | Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers | Phase 1 | Completed |
| NCT01457690 | 2011-10-01 | Study of the Absorption of Vitamin E Water-soluble Form (Pegylated) in the Familial Hypocholesterolemia With Chylomicron Retention | Phase 3 | Active, Not Recruiting |
| NCT01291433 | 2011-03-01 | Trial of Combined Pentoxifylline-tocopherol-clodronate vs Placebo in Radiation-induced Brachial Plexopathy | Phase 3 | Recruiting |
| NCT01314443 | 2011-01-01 | Impact of Smoking Cessation and γ-Tocopherol to Restore Vascular Endothelial Function | Phase 1/Phase 2 | Completed |
| NCT01329770 | 2010-12-01 | Safety and Efficacy Study of Antioxidants for the Treatment of the Fragile X Syndrome | Phase 2 | Active, Not Recruiting |
| NCT01822405 | 2010-07-01 | Treatment of Radiation-induced Fibrosis in the Upper Aerodigestive Tract Cancer by a Combination of Pentoxifylline-tocopherol and Hyperbaric Oxygen | Phase 2 | Recruiting |
| NCT01574313 | 2010-04-01 | Effect of Stellate Ganglion Block on Meniere's Disease | Phase 4 | Completed |
| NCT01061320 | 2010-01-01 | Efficacy of Alpha Tocopherol for Prevention of Contrast-induced Nephropathy in Chronic Kidney Disease (CKD) Patients | Phase 3 | Enrolling By Invitation |
| NCT00836368 | 2008-12-01 | In Vitro Basophil Responsiveness to Allergen Challenge After Gamma-tocopherol Supplementation in Allergic Asthmatics | Phase 1 | Completed |
| NCT00631085 | 2008-05-01 | Effect of Gamma Tocopherol Supplementation on Neutrophil Response to 20,000 EU of Clinical Center Reference Endotoxin in Normal Adults | Phase 1 | Completed |
| NCT01544192 | 2008-04-01 | Impact of Oral Versatile Antioxidants on Glaucoma Progression | Phase 3 | Completed |
| NCT00235716 | 2007-08-01 | A Randomized, Clinical Trial of Vitamin E and Memantine in Alzheimer's Disease | Phase 3 | Completed |
| NCT00466596 | 2007-03-01 | Effect of House Dust Mite Allergen Challenge in Persons Using 1200 mg Gamma Tocopherol Supplements | Phase 1 | Completed |
| NCT00386178 | 2006-10-01 | Safety Study of a Vitamin E Supplement in Normal Volunteers and Those With Both Allergy and Asthma | Phase 1 | Completed |
| NCT00237718 | 2006-04-01 | Provision of Antioxidant Therapy in Hemodialysis (PATH) Study | Phase 2 | Completed |
| NCT00678834 | 2006-03-01 | Human Tissue Distribution of Orally Supplemented Natural Vitamin E Tocotrienol | Phase 0 | Completed |
| NCT00308971 | 2006-03-01 | Tocopherols and Alpha Lipoic Acid Treatment Chronic Kidney Disease (TALAT) | Phase 2 | Completed |
| NCT00162526 | 2005-12-01 | Tocopherol is a Novel Treatment for Cancer Related Mucositis | Phase 2 | Withdrawn |
| NCT00655018 | 2003-01-01 | Effect of Vitamin E on Pediatric Nonalcoholic Fatty Liver Disease (NAFLD) | Phase 2/Phase 3 | Completed |
| NCT00188669 | 2002-07-01 | The Use of Pentoxifylline and Vitamin E in the Treatment of Chronic Breast Pain | Phase 2 | Terminated |
| NCT00188552 | 2002-07-01 | The Use of Pentoxifylline and Vitamin E in the Treatment of Late Radiation Related Injuries | Phase 2 | Terminated |
| NCT00119119 | 2002-02-01 | Efficacy and Safety of Pentoxyphilline and Tocopherol on the Fibrosis in Patients With Chronic Hepatitis C | Phase 3 | Terminated |
| NCT00410449 | 2001-05-01 | Oxidative Stress and Hemodialysis Access Failure | Phase 4 | Completed |
| NCT01594346 | 2000-09-01 | Multicenter Vitamin E Trial in Aging Persons With Down Syndrome | Phase 3 | Completed |
| NCT00114387 | 1996-07-01 | VEAPS: Vitamin E Atherosclerosis Prevention Study | Phase 2/Phase 3 | Completed |
| NCT01422317 | 1995-09-01 | Effects of High-dose n-3 Fatty Acids on Clinical Outcome and Serum Lipids - Omacor Following Acute Myocardial Infarction | Phase 3 | Completed |
| NCT00169845 | 1994-10-01 | Beta-carotene and Alpha-tocopherol Chemoprevention of Second Primary Malignancies in Head and Neck Cancer Patients | Phase 3 | Active, Not Recruiting |
| NCT00002586 | 1993-01-01 | 13-Cis Retinoic Acid With or Without Vitamin E for Prevention of Lung Cancer | Phase 2 | Completed |