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1 Indications & Usage Olanzapine For Injection Is An Atypical Antipsychotic Indicated For The: Treatment Of Acute Agitation Associated With Schizophrenia And Bipolar I Mania. ( 1.4 ) Efficacy Was Established In Three 1-Day Trials In Adults. ( 14.3 ) 1.4 Agitation Associated With Schizophrenia And Bipolar I Mania Olanzapine For Injection Is Indicated For The Treatment Of Acute Agitation Associated With Schizophrenia And Bipolar I Mania. Efficacy Was Demonstrated In 3 Short-Term (24 Hours Of Intramuscular Treatment) Placebo-Controlled Trials In Agitated Adult Inpatients With: Schizophrenia Or Bipolar I Disorder (Manic Or Mixed Episodes) [See Clinical Studies ( 14.3 )]. “psychomotor Agitation” Is Defined In Dsm-Iv As “excessive Motor Activity Associated With A Feeling Of Inner Tension.” Patients Experiencing Agitation Often Manifest Behaviors That Interfere With Their Diagnosis And Care, E.g., Threatening Behaviors, Escalating Or Urgently Distressing Behavior, Or Self-Exhausting Behavior, Leading Clinicians To The Use Of Intramuscular Antipsychotic Medications To Achieve Immediate Control Of The Agitation.
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