Application Nr Approved Date Route Status External Links
BLA125559 None Subcutaneous None Google , Wikipedia , PubMed , DailyMed , Raw OpenFDA , ECHA , ToxNet , JECFA , FAO , 21 CFR

Indications and Purposes

1 Indications And Usage Praluent Is A Pcsk9 (Proprotein Convertase Subtilisin Kexin Type 9) Inhibitor Antibody Indicated: To Reduce The Risk Of Myocardial Infarction, Stroke, And Unstable Angina Requiring Hospitalization In Adults With Established Cardiovascular Disease. ( 1.1 ) As Adjunct To Diet, Alone Or In Combination With Other Lipid-Lowering Therapies (E.g., Statins, Ezetimibe), For The Treatment Of Adults With Primary Hyperlipidemia (Including Heterozygous Familial Hypercholesterolemia) To Reduce Low-Density Lipoprotein Cholesterol Ldl-C. ( 1.2 ) 1.1 Prevention Of Cardiovascular Events Praluent ® Is Indicated To Reduce The Risk Of Myocardial Infarction, Stroke, And Unstable Angina Requiring Hospitalization In Adults With Established Cardiovascular Disease . 1.2 Primary Hyperlipidemia (Including Heterozygous Familial Hypercholesterolemia) Praluent Is Indicated As An Adjunct To Diet, Alone Or In Combination With Other Lipid-Lowering Therapies (E.g., Statins, Ezetimibe), For The Treatment Of Adults With Primary Hyperlipidemia To Reduce Low-Density Lipoprotein Cholesterol (Ldl-C).

All Formulated Excipients (0 Total)

None

Active Ingredients ( 1 Total)

Name Structure ZINC ID(s)
1. Alirocumab

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