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1 Indications And Usage Vabomere (Meropenem And Vaborbactam) Is A Combination Of Meropenem, A Penem Antibacterial, And Vaborbactam, A Beta-Lactamase Inhibitor, Indicated For The Treatment Of Patients 18 Years And Older With Complicated Urinary Tract Infections (Cuti) Including Pyelonephritis Caused By Designated Susceptible Bacteria. ( 1.1 ) To Reduce The Development Of Drug-Resistant Bacteria And Maintain The Effectiveness Of Vabomere And Other Antibacterial Drugs, Vabomere Should Be Used Only To Treat Or Prevent Infections That Are Proven Or Strongly Suspected To Be Caused By Susceptible Bacteria. ( 1.2 ) 1.1. Complicated Urinary Tract Infections (Cuti), Including Pyelonephritis Vabomere ® Is Indicated For The Treatment Of Patients 18 Years Of Age And Older With Complicated Urinary Tract Infections (Cuti) Including Pyelonephritis Caused By The Following Susceptible Microorganisms: Escherichia Coli , Klebsiella Pneumoniae , And Enterobacter Cloacae Species Complex. 1.2. Usage To Reduce The Development Of Drug-Resistant Bacteria And Maintain The Effectiveness Of Vabomere And Other Antibacterial Drugs, Vabomere Should Be Used Only To Treat Or Prevent Infections That Are Proven Or Strongly Suspected To Be Caused By Susceptible Bacteria. When Culture And Susceptibility Information Are Available, They Should Be Considered In Selecting Or Modifying Antibacterial Therapy. In The Absence Of Such Data, Local Epidemiology And Susceptibility Patterns May Contribute To The Empiric Selection Of Therapy.
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