1 Indications And Usage Duexis, A Combination Of The Nsaid Ibuprofen And The Histamine H 2 -Receptor Antagonist Famotidine, Is Indicated For The Relief Of Signs And Symptoms Of Rheumatoid Arthritis And Osteoarthritis And To Decrease The Risk Of Developing Upper Gastrointestinal Ulcers, Which In The Clinical Trials Was Defined As A Gastric And/or Duodenal Ulcer, In Patients Who Are Taking Ibuprofen For Those Indications. The Clinical Trials Primarily Enrolled Patients Less Than 65 Years Of Age Without A Prior History Of Gastrointestinal Ulcer. Controlled Trials Do Not Extend Beyond 6 Months [See Clinical Studies (14) , Use In Specific Populations (8.5) ] . Duexis, A Combination Of A Nonsteroidal Anti-Inflammatory Drug (Nsaid) Ibuprofen And The Histamine H 2 -Receptor Antagonist Famotidine, Is Indicated For The Relief Of Signs And Symptoms Of Rheumatoid Arthritis And Osteoarthritis And To Decrease The Risk Of Developing Upper Gastrointestinal Ulcers, Which In The Clinical Trials Was Defined As A Gastric And/or Duodenal Ulcer, In Patients Who Are Taking Ibuprofen For Those Indications. The Clinical Trials Primarily Enrolled Patients Less Than 65 Years Of Age Without A Prior History Of Gastrointestinal Ulcer. Controlled Trials Do Not Extend Beyond 6 Months. ( 1 )
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