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1 Indications And Usage Rinvoq Is A Janus Kinase (Jak) Inhibitor Indicated For The Treatment Of Adults With Moderately To Severely Active Rheumatoid Arthritis Who Have Had An Inadequate Response Or Intolerance To Methotrexate. ( 1 ) Limitation Of Use : Use Of Rinvoq In Combination With Other Jak Inhibitors, Biologic Dmards, Or With Potent Immunosuppressants Such As Azathioprine And Cyclosporine Is Not Recommended. ( 1 ) 1.1 Rheumatoid Arthritis Rinvoq ™ (Upadacitinib) Is Indicated For The Treatment Of Adults With Moderately To Severely Active Rheumatoid Arthritis Who Have Had An Inadequate Response Or Intolerance To Methotrexate. Limitation Of Use: Use Of Rinvoq In Combination With Other Jak Inhibitors, Biologic Dmards, Or With Potent Immunosuppressants Such As Azathioprine And Cyclosporine, Is Not Recommended.
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