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Indications And Usage Levonorgestrel And Ethinyl Estradiol Tablets, Usp Are Indicated For The Prevention Of Pregnancy In Women Who Elect To Use Oral Contraceptives As A Method Of Contraception. Oral Contraceptives Are Highly Effective. Table Ii Lists The Typical Accidental Pregnancy Rates For Users Of Combination Oral Contraceptives And Other Methods Of Contraception. The Efficacy Of These Contraceptive Methods, Except Sterilization, The Iud, And Norplant ® System, Depends Upon The Reliability With Which They Are Used. Correct And Consistent Use Of Methods Can Result In Lower Failure Rates. Emergency Contraceptive Pills: The Fda Has Concluded That Certain Combined Oral Contraceptives Containing Ethinyl Estradiol And Norgestrel Or Levonorgestrel Are Safe And Effective For Use As Postcoital Emergency Contraception. Treatment Initiated Within 72 Hours After Unprotected Intercourse Reduces The Risk Of Pregnancy By At Least 75%. 9 Lactation Amenorrhea Method: Lam Is A Highly Effective, Temporary Method Of Contraception. 10 Source: Trussell J. Contraceptive Efficacy. In: Hatcher Ra, Trussell J, Stewart F, Cates W, Stewart Gk, Kowel D, Guest F. Contraceptive Technology: Seventeenth Revised Edition. New York Ny: Irvington Publishers; 1998. % Of Women Experiencing An Unintended Pregnancy Within The First Year Of Use % Of Women Continuing Use At One Year 3 Method Typical Use 1 Perfect Use 2 (1) (2) (3) (4) Chance 4 85 85 Spermicides 5 26 6 40 Periodic Abstinence 25 63 Calendar 9 Ovulation Method 3 Sympto-Thermal 6 2 Post-Ovulation 1 Cap 7 Parous Women 40 26 42 Nulliparous Women 20 9 56 Sponge Parous Women 40 20 42 Nulliparous Women 20 9 56 Diaphragm 7 20 6 56 Withdrawal 19 4 Condom 8 Female (Reality) 21 5 56 Male 14 3 61 Pill 5 71 Progestin Only 0.5 Combined 0.1 Iud Progesterone T 2.0 1.5 81 Copper T380a 0.8 0.6 78 Lng 20 0.1 0.1 81 Depo-Provera ® 0.3 0.3 70 Levonorgestrel Implants (Norplant ® ) 0.05 0.05 88 Female Sterilization 0.5 0.5 100 Male Sterilization 0.15 0.10 100 In A Clinical Trial With Levonorgestrel And Ethinyl Estradiol Tablets, 1,477 Subjects Had 7,720 Cycles Of Use And A Total Of 5 Pregnancies Were Reported. This Represents An Overall Pregnancy Rate Of 0.84 Per 100 Women-Years. This Rate Includes Patients Who Did Not Take The Drug Correctly. One Or More Pills Were Missed During 1,479 (18.8%) Of The 7,870 Cycles; Thus All Tablets Were Taken During 6,391 (81.2%) Of The 7,870 Cycles. Of The Total 7,870 Cycles, A Total Of 150 Cycles Were Excluded From The Calculation Of The Pearl Index Due To The Use Of Backup Contraception And/or Missing 3 Or More Consecutive Pills.
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