CALCOBUTROL

Molecular Excipient

Mwt. LogP HBD HBA PSA RB CSP3
450.0 -3.8 6 10 186.0 10 0.83
CAS
151878238
UNII
J1A8830GE7
SYNONYMS
ZINC ID(s)
Availability
Present in 10 ZINC catalogs

Known Active Genes

There has not been any activity reported at 10μM or less for this excipient (per ChEBML)

Clinical Trials

This compound has been an intervention in the following clincial trials (per clinicaltrials.gov).
Code Date Title Phase Status
NCT02350426 2015-04-01 A Study to Assess Inflammation in Rheumatoid Arthritis Using Molecular Imaging Techniques Phase 1 Not Yet Recruiting
NCT02274246 2014-11-01 Validation of the Efficacy of the Tool GIMIAS® for the Assessment of Left Atrial Fibrosis in a Group of Healthy Volunteers (RESTORE-HV) Phase 1 Recruiting
NCT02135861 2014-07-01 A Method Validation Study for Evaluation of Novel Treatments Limiting Pulmonary Oedema in Cardiac Failure Phase 1 Recruiting
NCT01890434 2013-08-01 Gadobutrol/Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD) Including GSPECT (Gated Single Photon Emission Computed Tomography) Phase 3 Recruiting
NCT01890421 2013-07-01 Gadobutrol/Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD) Phase 3 Recruiting
NCT01660841 2012-09-01 Safety and Efficacy of Gadobutrol 1.0 Molar in Japanese Subjects for CNS Imaging Phase 3 Completed
NCT01655290 2012-08-01 Comparison of Gadobutrol and Gadobenate Dimeglumin for Delayed Enhancement Cardiac MRI Phase 2 Active, Not Recruiting
NCT01613417 2012-08-01 Comparison of Prohance® With Gadovist®/Gadavist™ in Magnetic Resonance Imaging (MRI) of the Brain Phase 4 Completed
NCT01544166 2012-05-01 Gadobutrol Pharmacokinetic and Safety Study in Pediatric Subjects Aged <2 Years (Term Newborn Infants to Toddlers 23 Months of Age Inclusive) Phase 1 Completed
NCT01344447 2011-05-01 Gadobutrol Enhanced MRA of the Supra-aortic Vessels Phase 3 Completed
NCT01344460 2011-05-01 Gadobutrol Enhanced MRA of the Renal Arteries Phase 3 Completed
NCT01104584 2010-05-01 Efficacy and Safety of Gadobutrol 1.0 Molar (Gadovist) for Breast Magnetic Resonance Imaging (MRI) Phase 3 Completed
NCT01067976 2010-02-01 Efficacy and Safety of Gadobutrol 1.0 Molar (Gadovist) for Breast MRI Phase 3 Completed
NCT01050829 2010-01-01 Gadobutrol Magnevist-controlled Body Study Phase 3 Completed
NCT00828737 2008-12-01 Safety of Gadovist in Renally Impaired Patients Phase 4 Completed
NCT00709852 2008-06-01 Safety and Efficacy of Gadobutrol 1.0 Molar (Gadavist) in Patients for Central Nervous System (CNS) Imaging Phase 3 Completed
NCT00764387 2008-03-01 Contrast Enhanced MRI of the CNS - Patients With Known Cerebral Neoplastic Lesions. Phase 4 Completed
NCT00623467 2007-12-01 Safety and Efficacy of Gadobutrol 1.0 Molar ( Gadavist ) in Patients for Central Nervous System (CNS) Imaging Phase 3 Completed
NCT00522951 2007-08-01 SH L 562BB Phase II/III Dose Justification and Gadoteridol-controlled Comparative Study Phase 3 Completed
NCT00468819 2007-05-01 A Study of Magnetic Resonance Imaging (MRI) With Gadavist in Children Phase 1 Completed
NCT00395733 2006-10-01 Efficacy and Safety Study to Evaluate Gadavist (Gadobutrol) as Contrast Agent in Magnetic Resonance Imaging (MRI) of Vascular Diseases in Chinese Patients Phase 3 Completed
NCT00395460 2006-09-01 Efficacy and Safety Study to Evaluate Gadavist (Gadobutrol) as Contrast Agent in Magnetic Resonance Imaging (MRI) of Brain or Spine Diseases in Chinese Patients Phase 3 Completed
NCT00862459 2005-08-01 Dose Finding Study of Gadavist in Central Nervous System (CNS) Magnetic Resonance Imaging (MRI) Phase 2 Completed
NCT01490294 2004-03-01 Myocardial Perfusion MRI Phase 2 Completed

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Dosages

Route Formulation Per Unit Dose
Intravenous Solution, Injection 0.04%W/W

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Usage Over Time

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