ALANINE

Molecular Excipient

Mwt. LogP HBD HBA PSA RB CSP3
89.0 -0.6 2 2 63.0 1 0.67
UNII
OF5P57N2ZX
CAS
56-41-7
SYNONYMS
  • Alanine
  • L-2-Aminopropanoic Acid
  • L-Alanine
  • Alanine [inn]
  • Alanine [usan]
  • Alanine [ep]
  • Alanine [usp]
  • L-Alanine [jan]
  • Alanine [mi]
  • Alanine [inci]
  • L-Alanine [fcc]
  • Alanine [ii]
  • Alanine [hsdb]
  • L-Alanine [usp-Rs]
  • Alanine [who-Dd]
  • Alanine [vandf]
  • Nsc-206315
ZINC ID(s)
Availability
Present in 101 ZINC catalogs

Known Active Genes

There has not been any activity reported at 10μM or less for this excipient (per ChEBML)

Clinical Trials

This compound has been an intervention in the following clincial trials (per clinicaltrials.gov).
Code Date Title Phase Status
NCT00008801 hOKT3gamma1 (Ala-Ala) for the Prevention of Human Islet Allograft Failure Phase 1/Phase 2 Active, Not Recruiting
NCT00309439 ALA and Prostate Cancer Phase 2 Active, Not Recruiting
NCT02145949 2015-01-01 Mechanistic Approach to Preventing Atrophy and Restoring Function in Older Adults Phase 2 Recruiting
NCT02281136 2014-12-01 MUSE Study of Levulan Kerastick Phase 2 Not Yet Recruiting
NCT02209012 2014-08-01 Twelve Month Follow-Up of CP0108 Phase 3 Recruiting
NCT02137785 2014-05-01 Safety and Efficacy Study of Photodynamic Therapy With Levulan Kerastick + Blue Light for Actinic Keratoses on the Upper Extremities Phase 3 Recruiting
NCT02144077 2014-01-01 Safety and Efficacy Study for the Treatment of Non-Aggressive Basal Cell Carcinoma With Photodynamic Therapy Phase 3 Recruiting
NCT01944059 2013-11-01 Theramine® in the Prevention of Migraine Headache Phase 4 Active, Not Recruiting
NCT01893203 2013-08-01 Treating Actinic Keratoses With Natural Daylight PDT: Comparing Two Light Sensitizers (ALA and MAL) Phase 4 Completed
NCT01838694 2013-07-01 Double-Blinded, Randomized, Placebo-Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Biochemical Activity of Intravenous Cpn10 Administration in Subjects With Mild to Moderate SLE. Phase 1/Phase 2 Recruiting
NCT01898416 2013-06-01 Safety and Efficacy Study Using 5-ALA Oral Administration as an Adjuvant Therapy on the Rate of Local Tumor Recurrence in Patients Who Have Desmoids Tumors Phase 2 Recruiting
NCT01811121 2013-02-01 MEDICO-ECONOMIC EVALUATION OF SURGERY GUIDED BY FLUORESCENCE FOR THE OPTIMIZATION OF RESECTION OF GLIOBLASTOMAS Phase 3 Recruiting
NCT01522677 2012-01-01 A Study of Neoadjuvant Photodynamic Immunomodulation for Colon Cancer Phase 1/Phase 2 Recruiting
NCT01478126 2012-01-01 Effects of Glutamine in Ischemic Heart Disease Patients Following Cardiopulmonary Bypass Phase 3 Completed
NCT01475955 2011-12-01 Short-incubation Levulan Photodynamic Therapy Versus Vehicle for Face/Scalp Actinic Keratosis (AK) Phase 2 Completed
NCT01458587 2011-11-01 Levulan PDT Versus Vehicle for Extremity Actinic Keratoses (AK) Phase 2 Completed
NCT01445691 2011-09-01 More Complete Removal of Malignant Brain Tumors by Fluorescence-Guided Surgery Phase 2 Recruiting
NCT01310868 2011-05-01 Gliadel Wafer and Fluorescence-Guided Surgery With 5-ALA Followed by Radiation Therapy And Temozolomide in Treating Patients With Primary Glioblastoma Phase 2 Active, Not Recruiting
NCT01267253 2011-04-01 Brivanib in Treating Patients With Persistent or Recurrent Cervical Cancer Phase 2 Suspended
NCT00628381 2011-01-01 L-citrulline Supplementation During Sepsis Phase 3 Not Yet Recruiting
NCT01253668 2010-11-01 Brivanib Metastatic Renal Cell Carcinoma Phase 2 Completed
NCT01502280 2010-11-01 Fluorescence-guided Surgery for Low- and High-grade Gliomas Phase 3 Recruiting
NCT01459393 2010-11-01 Comparison Between 5-aminolevulinic Acid Photodynamic Therapy Versus Cryotherapy for Actinic Keratosis Treatment Phase 3 Completed
NCT01611584 2010-06-01 A Proof of Principle Study of Aminolevulinic Acid (ALA) - Induced Fluorescence Detection in Resectable Non-Small Cell Lung Cancer Phase 1 Withdrawn
NCT01051999 2010-02-01 Glutamine Supplementation in Cystic Fibrosis Phase 2 Completed
NCT00888173 2009-07-01 Brivanib Alaninate in Treating Patients With Recurrent or Persistent Endometrial Cancer Phase 2 Active, Not Recruiting
NCT00798252 2009-03-01 Ascending Multiple-Dose Study of Brivanib Alaninate in Combination With Chemotherapeutic Agents in Subjects With Advanced Cancers Phase 1 Active, Not Recruiting
NCT01259544 2009-01-01 BreathID® Test: A Non-invasive Modality to Detect Pancreatic Exocrine Insufficiency Phase 2 Completed
NCT00948324 2008-06-01 Effect of Intensive Therapy Associated With CSII on β-cell Function With Newly Diagnosed Type 2 Diabetes Phase 4 Enrolling By Invitation
NCT00640471 2008-05-01 Cetuximab With or Without Brivanib in Treating Patients With K-Ras Wild Type Tumours and Metastatic Colorectal Cancer Phase 3 Completed
NCT01185210 2007-09-01 Investigation of Alanine in Fructose Intolerance: A Dose Ranging Study Phase 2 Recruiting
NCT00706433 2007-03-01 Light Dose Ranging Study of Photodynamic Therapy (PDT) With Levulan + Blue Light Versus Vehicle + Blue Light in Severe Facial Acne Phase 2 Completed
NCT00378508 2006-09-01 Anti-CD3 mAb Treatment of Recent Onset Type 1 Diabetes Phase 2 Active, Not Recruiting
NCT00239720 2006-03-01 hOKT3gamma1 (Ala-Ala) for the Treatment of Psoriatic Arthritis Phase 2 Terminated
NCT00073255 2003-06-01 Safety and Pharmacokinetics (PK) of hOKT3g1 (Ala-Ala) in Type 1 Diabetes Mellitus (T1DM) Phase 1 Completed
NCT00164268 2002-10-01 Ke Ala Lokahi Demonstration Project for Sexual and Domestic Violence Prevention Phase 1 Completed
NCT00806572 2002-05-01 Treatment With hOKT3gamma1(Ala-Ala) in T1DM Phase 2 Terminated
NCT00285194 2000-04-01 hOKT3γ1 (Ala-Ala) Combined With Sirolimus and Delayed Tacrolimus in Type 1 Diabetic Islet Allograft Recipients Phase 1/Phase 2 Completed
NCT00241670 1999-10-01 Fluorescence-guided Resection of Malignant Gliomas With 5-Aminolevulinic Acid Phase 3 Completed
NCT00410839 1999-06-01 Studies of the Prevention of Atrial Fibrillation by ALA Phase 2 Active, Not Recruiting

(Browse) Purchasable Analogs in ZINC

Products Using Alanine

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APIs Products incorporating these APIs
Alcohol Anti-Aging Hand Sanitizer
Sus Scrofa Skin Pige Ll Real Skin Neck Pack , Pige Ll Real Skin Eye , Pige Ll Real Skin Mask Pack
Octinoxate , Oxybenzone Cyzone Cy Soluxion Desmanchadora Fps 15 , Natural Care Concha De Nacar And Rosa Mosqueta Crema Facial Fps 15 Para Una Apariencia Mas Clara Fm , Esika Natural Care Concha De Nacar And Rosa Mosqueta Facial Fps 15 , Cyzone Cy Soluxion Aclaradora Fps 15 , Esika Natural Care
Glycerin Cliv Barrier Power Ampoule , Correct Combo , Revitalizing Facial Foam , V Shaping Ampoule , Anypack Multi Active Hydroge L Eye , Anypack Gold Season Second Skin Hydro Face Mask , Colloidal Iodine , Repiel Timeless Aqua Shot Bio Mask , Renovating Regenerating Nourishing Cream , Renovating Regenerating Moisturizing Cream , Tonymoly Timeless Gf-Factor Toner , Jci Mn Colloidal Iodine Cream
Adenosine Niveola 3d Animal Cat Mask Pack , Dr. Althea Water Glow Aqua Ampoule Mask
Menthol , Salicylic Acid , Panthenol Cellapy Haircell Meso Tonic
Avobenzone , Octinoxate , Ensulizole No7 Rebalancing Day Fluid Sunscreen Spf 15 , No7 Rebalancing Day Fluid Sunscreen Spf 15
Witch Hazel Aqua Barrier Level Up , Aqua Barrier Hydro Softener , Freeze 24 7 Intense Hydrating Face Mask , Dr. Dream Advanced Eye Treatment , Dr. Dream Advanced Facial Treatment Toner , Dr. Dream Cold Plazma Whitening , Dr. Dream Advanced Facial Treatment Serum , Dr. Dream Advanced Facial Treatment Serum , Leaders Coconut Moisturizing Recovery Mask , Aqua Barrier Lotus Essence Mist , Cellcurin Hair Regen Ampoule , Leaders Insolution Coconut Moisturizing Recovery Mask , Leaders Mediu 2 Step Double Effect Moisturizing Mask , Aquaringer Treatment Mask
Avobenzone , Octinoxate , And Oxybenzone Zo Skin Health Oraser Anti-Aging Hand Care Program Correct, Protect And Prevent Aging Hands
Octinoxate Crystal Miracle Multi , Lbel Replenishing Foundation Spf 14 (claire 1) - Beige , Lbel Supremacie Teint
Octisalate , Octinoxate , Titanium Dioxide Snp Animal Tiger Long-Lasting Cover Cushion , Snp Animal Panda Luminous Cover Cushion
Octinoxate , Titanium Dioxide Ceramide Lift And Firm Makeup Broad Spectrum Sunscreen Spf 15 Warm Bisque , Ceramide Lift And Firm Makeup Broad Spectrum Sunscreen Spf 15 Perfect Beige , Ceramide Lift And Firm Makeup Broad Spectrum Sunscreen Spf 15 Toasty Beige , Shimmery Sun , Ceramide Lift And Firm Makeup Broad Spectrum Sunscreen Spf 15 Spice , Sun Essential , Shimmery Sun , Ceramide Lift And Firm Makeup Broad Spectrum Sunscreen Spf 15 True Beige , Ceramide Lift And Firm Makeup Broad Spectrum Sunscreen Spf 15 Java , Ceramide Lift And Firm Makeup Broad Spectrum Sunscreen Spf 15 Gentle Beige , Shimmery Sun , Sun Essential , Sun Defense Canyonranch , Sun Defense Canyon Ranch , Ceramide Lift And Firm Makeup Broad Spectrum Sunscreen Spf 15 Cognac , Ceramide Lift And Firm Makeup Broad Sprectrum Sunscreen Spf 15 Sandstone , Ceramide Lift And Firm Makeup Broad Spectrum Sunscreen Spf 15 Cameo , Ceramide Lift And Firm Makeup Broad Spectrum Sunscreen Spf 15 Vanilla Shell , Ceramide Lift And Firm Makeup Broad Spectrum Sunscreen Spf 15 Cream , Ceramide Lift And Firm Makeup Broad Spectrum Sunscreen Spf 15 Toast , Ceramide Lift And Firm Makeup Broad Spectrum Sunscreen Spf 15 Warm Bronze , Ceramide Lift And Firm Makeup Broad Spectrum Sunscreen Spf 15 Warm Sunbeige , Ceramide Lift And Firm Makeup Broad Spectrum Sunscreen Spf 15 Bisque , Ceramide Lift And Firm Makeup Broad Spectrum Sunscreen Spf 15 Buff , Ceramide Lift And Firm Makeup Broad Spectrum Sunscreen Spf 15 Cocoa , Ceramide Lift And Firm Makeup Broad Spectrum Sunscreen Spf 15 Warm Honey , Ceramide Lift And Firm Makeup Broad Spectrum Sunscreen Spf 15 Beige , Ceramide Lift And Firm Makeup Broad Spectrum Sunscreen Spf 15 Mocha
Zinc Oxide , Titanium Dioxide Premium Gold Mineral Bb , Missha M Signature Real Complete Bb Spf25 Pa Plus Plus , Dr.g Age Defense Bb Spf50 Plus Pa Plus Plus , Missha M Signature Real Complete Bb Honey Beige , Aqua Aura Moist Finish Pact , Premium Gold Mineral Bb
Zinc Oxide , Octisalate , Octinoxate , Titanium Dioxide Dr. Jart Bb Get Ready
Glycerin , Yellow Wax Tonymoly Intense Care Gold Syn-Ake Wrinkle Cream
Octisalate , Homosalate , Octocrylene , Avobenzone , Octinoxate Silky And Clear Sunscreen
Avobenzone , Octinoxate , Oxybenzone Oraser Daily Hand Repair Broad-Spectrum Spf 20 Sunscreen
Avobenzone , Octinoxate Day Cream Mattifying Hydrator Spf 25 , Day Cream Replenishing Hydrator Spf 25
Octisalate , Octinoxate , Titanium Dioxide , Oxybenzone Guinot Skin Defense Spf 15 Face
Niacinamide Mineral Homme White , Mineral Homme White Toner , Hanskin Real Complexion
Adenosine , Niacinamide Neogen Dermalogy White Truffle Serum In Oi L Drop , Vita Volu Volume Booster , Vitabrid C12 Sensitive Spot Pow Der Serum , Neogen Agecure 3d Lifting Wrinkle Neck Mask , Neogen Agecure 3d Lifting Compression Span Tex Mask
Adenosine , Niacinamide , Panthenol Vita Volu 101 Essence
Dimethicone Bellido Hydro Secret Ampoule , Skinpia 10 Skin Shield Renewal , G9 Whitening , Mederma Pm
Zinc Oxide W.lab W-Snow Cc Cushion 21 Snow Light , W.lab W-Snow Cc Cushion 23 Snow Beige , G9 Whitening Skin
Glycerin , Allantoin , Hydroxyethyl Cellulose (100 Mpa.s At 2%) Jenacell Supercell Serum
Levomenol Neogen Dermalogy White Truffle Laycure Oi L
Bos Taurus Hypothalamus , Bos Taurus Pituitary Gland Meditrend Td-Tropin Plus
Salicylic Acid St. Ives Blemish And Blackhead Facial , Blemish Correcting Serum Sensitive , Obeo Hair , Pharma Clear Moisturizer
Ascorbic Acid Dr Cellapy Sr Premium
Pyrithione Zinc Satinique Anti-Dandruff For Dry, Irritated Scalp
Octisalate , Homosalate , Octocrylene , Avobenzone Anti-Wrinkle Day Cream Suncreen Broad Spectrum Spf 30 , Line Interception Power Duo Day Cream Suncreen Broad Spectrum Spf 30 , Line Interception Power Duo Day Cream Sunscreen Broad Spectrum Spf 30
Glycerin , Allantoin Correct Essential Activator
Octisalate , Octocrylene , Avobenzone Ahava Active Deadsea Minerals Time To Hydrate Essential Moisturizing Broad Spectrum Spf15 , Ahava Active Deadsea Minerals Time To Energize Age Control Moisturizing Broad Spectrum Spf15
Octinoxate , Titanium Dioxide , Oxybenzone Lumene Time Freeze Targeted Dark Spot Corrector Sunscreen Spf 30
Titanium Dioxide Oi Lin Natural Sunscreen Spf 30 , Missha M Watery B.b Spf 27
Zinc Oxide , Octinoxate , Titanium Dioxide Dr. Jart Bb Boys Be Bold , Iope Air Cushion Flawless 21n , Iope Air Cushion Perfection C13 , Amorepacific Time Response Skin Renewal No. 100 , Iope Air Cushion Matte Longwear C13 , Iope Air Cushion Sheer 23w
Glycerin , Niacinamide Madeca Derma Mask , Madeca Derma Mask Ii
Dimethicone , Glycerin Tonymoly Timeless Gf-Factor Emulsion , Tonymoly Timeless Gf-Factor Cream , Tonymoly Intense Care Gold Syn-Ake Wrinkle Perfector
Triclosan Antibacterial , Antibacterial , Antibacterial
Allantoin Perfect Calming Serum

Dosages

Route Formulation Per Unit Dose
Iv(infusion) Solution, Injection 0.21%

More Information

Usage Over Time

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