BENZOIC ACID

Molecular Excipient

Mwt. LogP HBD HBA PSA RB CSP3
121.0 0.1 0 2 40.0 1 0.0
UNII
8SKN0B0MIM
CAS
65-85-0
SYNONYMS
  • Benzoic Acid
  • Phenylformic Acid
  • Dracylic Acid
  • Benzenecarboxylic Acid
  • Benzoicum Acidum
  • Fema No. 2131
  • Benzoic Acid [ep]
  • Benzoic Acid [usp]
  • Benzoicum Acidum [hpus]
  • Benzoic Acid [fhfi]
  • Benzoic Acid [mart.]
  • Benzoic Acid [mi]
  • Benzoic Acid [green Book]
  • Benzoic Acid [inci]
  • Benzoic Acid [fcc]
  • Benzoate
  • Benzoic Acid [ii]
  • Benzoic Acid [hsdb]
  • Benzoic Acid [usp-Rs]
  • Benzoic Acid [who-Dd]
  • Benzoic Acid [vandf]
  • Glycopyrronium Bromide Impurity D [ep]
  • Benzoic Acid (e 210)
  • B A
  • Nsc-149
  • Benzeneformic Acid
  • Benzenemethanoic Acid
  • Carboxybenzene
  • E-210
  • Ins-210
  • Ins No.210
  • Benzoic Acid [who-Ip]
  • Acidum Benzoicum [who-Ip Latin]
  • Vevovitall
  • Phenylcarboxylic Acid
  • Menno-Florades
ZINC ID(s)
Availability
Present in 97 ZINC catalogs

Known Active Genes

This compound has been observed to have activity at 10μM or less against the following gene(s).
Name Description Classification
DAO D-amino-acid oxidase Enzyme / Enzyme-Other

Clinical Trials

This compound has been an intervention in the following clincial trials (per clinicaltrials.gov).
Code Date Title Phase Status
NCT02111200 2014-09-01 Comparative Efficacy of Phenylbutyrate (PBA) vs. Benzoate in Urea Cycle Disorders Phase 4 Recruiting
NCT02146209 2014-06-01 Study to Determine the Equivalence of Three Products Containing Metronidazole Benzoate. Phase 1 Completed
NCT02026947 2014-02-01 Sodium Benzoate for Treatment of Attenuated/Transient Psychosis. A Randomized Placebo-controlled Trial. Phase 2 Withdrawn
NCT01908192 2013-11-01 Adaptive Phase II Study to Evaluate the Safety & Efficacy of Sodium Benzoate as an Add-on Treatment for Schizophrenia in Adolescents Phase 2/Phase 3 Recruiting
NCT01004263 2009-12-01 A Study to Evaluate the Safety and Tolerability of Rizatriptan for Long Term Treatment of Acute Migraine in Children and Adolescents (MK-0462-086 AM3) Phase 3 Completed
NCT00812006 2009-03-01 A Study of Rizatriptan for the Treatment of Acute Migraine in Patients on Topiramate for Migraine Prophylaxis Phase 3 Completed
NCT00604812 2007-12-01 Drug Study in Pediatric Subjects With Migraines (MK0462-083 AM1) Phase 1 Completed
NCT00597909 2007-12-01 Efficacy and Safety Study of Ammonul® in Patients With Grade 3 or 4 Hepatic Encephalopathy Phase 2 Withdrawn
NCT00516737 2007-10-01 Study to Test Rizatriptan in the Early Treatment of Acute Migraine (0462-081) Phase 3 Completed
NCT01938183 2006-11-01 Full-mouth Periodontal Debridement and Metronidazole Gel in Patients With Chronic Periodontitis Phase 2 Completed
NCT00111709 2005-06-01 Study to Test a Marketed Drug in the Treatment of Menstrual Migraine (0462-071) Phase 3 Completed
NCT00111722 2005-05-01 Study to Test a Marketed Drug in the Treatment of Menstrual Migraine (0462-072) Phase 3 Completed
NCT00095004 2004-10-01 Study to Test an Approved Product in the Early Treatment of Migraine (0462-066) Phase 3 Completed
NCT00092963 2004-08-01 Study to Test an Approved Product in the Early Treatment of Migraine (0462-065) Phase 3 Completed
NCT00898677 1995-09-01 Rizatriptan 5 mg and 10 mg, Sumatriptan 100 mg, and Placebo Comparison Study (0462-030) Phase 3 Completed
NCT00897104 1995-08-01 MK0462 5 mg, Sumatriptan 50 mg, and Placebo Comparison Study (0462-029) Phase 3 Completed
NCT00899379 1995-04-01 Treatment of Multiple Attacks of Acute Migraine (0462-025) Phase 3 Completed
NCT00897949 1995-03-01 MK0462 in Treatment of Migraine With Recurrence (MK0462-022) Phase 3 Completed
NCT00004767 1985-01-01 Phase II Study of Sodium Phenylbutyrate, Sodium Benzoate, Sodium Phenylacetate, and Dietary Intervention for Urea Cycle Disorders Phase 2 Completed

(Browse) Purchasable Analogs in ZINC

Functions of Benzoic Acid

Pres - Chemical preservative

Regulatory Status of Benzoic Acid

Gras - Generally recognized as safe.

Products Using Benzoic Acid

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APIs Products incorporating these APIs
Zolpidem Tartrate Zolpimist(RX) , Zolpimist(RX)
Diazepam Diazepam(RX)
Nonoxynol-9 Today Vaginal Contraceptive(OTC)
Acetaminophen , Caffeine , Aspirin Excedrin Migraine(OTC) , Excedrin Migraine(OTC) , Excedrin Migraine Geltabs(OTC) , Excedrin Migraine(OTC)
Miconazole Nitrate Miconazole 7(OTC) , Miconazole Nitrate(OTC) , Miconazole 7(OTC) , Monistat 7 Combination Pack 7-Day Pre-Filled Applicators(OTC) , Miconazole 7(OTC) , Sunmark Miconazole 7(OTC) , Smart Sense 7 Day Treatment(OTC) , Smart Sense Miconazole 7(OTC) , Sunmark Miconazole 7(OTC) , Miconazole Nitrate(OTC) , Miconazole 7(OTC) , Miconazole 7(OTC) , Miconazole Nitrate(OTC) , Monistat 7 With Reusable Applicator(OTC) , Monistat 7 7-Day Disposable Applicators(OTC) , Good Sense Miconazole 7(OTC) , Miconazole 7(OTC) , Topcare Miconazole 7(OTC) , Signature Care Miconazole 7(OTC) , Equaline Miconazole 7(OTC) , Monistat 3 3-Day Pre-Filled Applicators(OTC) , Miconazole 7(OTC) , Miconazole 7(OTC) , Harris Teeter Miconazole 7(OTC) , Miconazole 7(OTC) , Monistat 7 Combination Pack Triple Action(OTC) , Miconazole 7(OTC) , Miconazole 7(OTC) , Up And Up Miconazole 7(OTC) , Miconazole 7(OTC) , Miconazole 7(OTC) , Miconazole 7(OTC) , Miconazole 7(OTC) , Good Neighbor Pharmacy Miconazole 7(OTC) , Good Sense Miconazole 7(OTC) , Miconazole 7(OTC) , Healthy Accents Miconazole 7(OTC) , Miconazole 7(OTC)
Risperidone Risperidone(DISCN) , Risperidone(RX) , Risperidone(RX) , Risperidone(RX)
Dextroamphetamine Sulfate Dextroamphetamine(RX)
Tretinoin , Avobenzone , Octinoxate , Octisalate And Titanium Dioxide Tretinopak(RX)
Methadone Hydrochloride Methadone Hydrochloride(RX) , Methadone Hydrochloride(RX)
Loperamide Hydrochloride Good Neighbor Pharmacy Anti Diarrheal(OTC) , Anti Diarrheal(OTC) , Rexall Anti Diarrheal(OTC) , Loperamide Hydrochloride(OTC) , Loperamide Hydrochloride(OTC) , Loperamide Hydrochloride(OTC)
Econazole Nitrate Econazole Nitrate(RX) , Econazole Nitrate(RX) , Econazole Nitrate(RX) , Econazole Nitrate(RX) , Econazole Nitrate(RX) , Econazole Nitrate(RX) , Econazole Nitrate Cream(RX) , Econazole Nitrate(RX)
Fluoxetine Hydrochloride Fluoxetine(RX) , Fluoxetine(RX) , Fluoxetine(RX)

Dosages

Route Formulation Per Unit Dose
Im - Iv Injection
Intramuscular Solution, Injection
Intravenous Solution, Injection
Irrigation Solution
Rectal Gel
Rectal Suspension
Topical Emulsion, Cream
Topical Gel
Topical Lotion
Topical Solution
Vaginal Emulsion, Aerosol Foam
Vaginal Emulsion, Cream
Vaginal Suppository
Intramuscular Injection
Iv(infusion) Injection
Topical Suppository
Topical Suppository, Insert
Vaginal Sponge 3MG
Oral Concentrate
Oral Liquid
Oral Solution
Oral Solution, Elixir
Oral Solution, Liquid
Oral Spray
Oral Suspension
Oral Syrup
Oral Emulsion
Oral Tablet, Coated
Oral Tablet, Film Coated

More Information

Usage Over Time

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