BUTYLATED HYDROXYTOLUENE

Molecular Excipient

Mwt. LogP HBD HBA PSA RB CSP3
220.0 4.3 1 1 20.0 0 0.6
UNII
1P9D0Z171K
CAS
128-37-0
SYNONYMS
  • Butylated Hydroxytoluene
  • Bht
  • Nsc-6347
  • Fema No. 2184
  • Butylhydroxytoluene
  • Butylhydroxytoluene [ep]
  • Butylated Hydroxytoluene [fhfi]
  • Butylated Hydroxytoluene [mart.]
  • Butylated Hydroxytoluene [mi]
  • Bht [inci]
  • Bht [fcc]
  • Butylated Hydroxytoluene [ii]
  • Butylated Hydroxytoluene [hsdb]
  • Butylated Hydroxytoluene [usp-Rs]
  • Butylated Hydroxytoluene [who-Dd]
  • Butylated Hydroxytoluene [vandf]
  • Butylated Hydroxytoluene (e 321)
  • Butylated Hydroxytoluene [nf]
  • Ins-321
  • Ins No.321
  • E-321
  • Butylated Hydroxytoluene [who-Ip]
  • Butylhydroxytoluenum [who-Ip Latin]
  • Kerabit
ZINC ID(s)
Availability
Present in 77 ZINC catalogs

Known Active Genes

This compound has been observed to have activity at 10μM or less against the following gene(s).
Name Description Classification
CA2 Carbonic anhydrase 2 Enzyme / Enzyme-Other

Clinical Trials

This compound has been an intervention in the following clincial trials (per clinicaltrials.gov).
Code Date Title Phase Status
NCT02220673 2009-11-01 Serial Lung Function Measurements in Healthy and Mild Asthmatic Adults After Oral Inhalation of Ethanolic Solutions Containing Two Concentrations of the Excipient Butylated Hydroxytoluene (BHT) Administered With the Respimat® B (RMT-B) Phase 1 Completed
NCT02221375 2008-06-01 Safety, Tolerability and Pharmacokinetics of Multiple Rising Doses of Butylated Hydroxytoluene and BI 54903 XX Via Respimat® Soft MistTM Inhaler B in Healthy Male Volunteers Phase 1 Completed
NCT00453375 2006-10-01 Phase 1 Study of BHT-3021 in Subjects With Type 1 Diabetes Mellitus Phase 1 Completed
NCT00382629 2006-02-01 BHT-3009 Immunotherapy in Relapsing Remitting Multiple Sclerosis Phase 2 Completed
NCT00103974 2004-07-01 Immunotherapy With BHT-3009 Alone or Combined With Atorvastatin in Patients With Multiple Sclerosis Phase 1 Completed

(Browse) Purchasable Analogs in ZINC

Products Using Butylated Hydroxytoluene

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APIs Products incorporating these APIs
Tretinoin Tretinoin(RX) , Renova(RX) , Tretinoin(RX) , Tretinoin(RX) , Tretinoin(RX) , Tretinoin(RX) , Retin-A(RX) , Zo Complex A Tretinoin (emollient)(RX) , Refissa Tretinoin (emollient)(RX) , Tretinoin(RX) , Tretinoin(RX) , Retin-A(RX) , Refissa(RX) , Tretinoin(RX) , Tretinoin(RX) , Tretinx(RX) , Tretinoin(RX) , Tretinoin Gel(RX) , Tretinoin(RX) , Avita(RX) , Renova(RX) , Tretinoin(RX) , Tretinoin Gel Microsphere(RX) , Tretinoin Cream(RX) , Tretinoin(RX) , Tretinoin(RX)
Metoclopramide Hydrochloride Metoclopramide Hydrochloride(RX) , Metoclopramide Hydrochloride(RX) , Metoclopramide Hydrochloride(RX)
Exemestane Exemestane(RX)
Deutetrabenazine Austedo(RX)
Betamethasone Dipropionate Sernivo(RX)
Ibuprofen , Hydrocodone Bitartrate Hydrocodone Bitartrate And Ibuprofen(RX)
Enzalutamide Xtandi(RX)
Tazarotene Tazorac(RX)
Oxymetazoline Hydrochloride Rhofade(RX)
Efinaconazole Jublia(RX)
Paricalcitol Paricalcitol(RX) , Paricalcitol(RX)
Tretinoin , Clindamycin Phosphate Veltin(RX) , Clindamycin Phosphate And Tretinoin(RX)
Mechlorethamine Valchlor(RX)
Fluorouracil Tolak(RX) , Tolak(RX)
Minoxidil Womens Rogaine Unscented(OTC) , Harmon Face Values Minoxidil Mens(OTC) , Renewal For Men(OTC) , Good Neighbor Pharmacy Hair Regrowth Treatment For Men(OTC) , Hair Regrowth Treatment For Men(OTC) , Mens Rogaine Minoxidil - Unscented Formula(OTC) , Minoxidil(OTC) , Signature Care Hair Regrowth Treatment For Women(OTC) , Minoxidil(OTC) , Smart Sense Hair Regrowth(OTC) , Members Mark Hair Regrowth Treatment(OTC) , Core Values Minoxidil(OTC) , Hair Regrowth Treatment(OTC) , Signature Care Hair Regrowth Treatment For Men(OTC) , Up And Up Minoxidil(OTC) , Up And Up Hair Regrowth Treatment For Men(OTC) , Daylogic For Men(OTC) , Kirkland Signature Minoxidil(OTC) , Minoxidil Foam(OTC) , Careone Hair Regrowth Treatment(OTC) , Image Essentials Hair Regrowth Treatment For Men(OTC) , Good Sense Hair Regrowth Treatment(OTC) , Members Mark Minoxidil(OTC) , Equaline Hair Regrowth Treatment For Men(OTC) , Minoxidil(OTC) , Minoxidil(OTC) , Simply Right Minoxidil(OTC) , Leader Hair Regrowth Treatment(OTC) , Hair Regrowth Treatment For Men(OTC) , Hair Regrowth Treatment For Men(OTC) , Hair Regrowth Treatment(OTC) , Womens Rogaine Unscented(OTC) , Equate Hair Regrowth Treatment(OTC)
Cetirizine Hydrochloride Cetirizine(OTC) , Cetirizine(OTC)
Miconazole Nitrate Miconazole Nitrate(OTC) , Miconazole 7(OTC) , Miconazole Nitrate(OTC)
Azithromycin Monohydrate Azithromycin(RX) , Azithromycin(RX) , Azithromycin(RX) , Azithromycin(RX) , Azithromycin(RX) , Azithromycin(RX) , Azithromycin(RX) , Azithromycin(RX) , Azithromycin(RX) , Azithromycin(RX) , Azithromycin(RX) , Azithromycin(RX) , Azithromycin(RX) , Azithromycin(RX)
Permethrin Permethrin(RX) , Permethrin(RX) , Permethrin(RX)
Luliconazole Luzu(RX)
Terbinafine Lamisil At Antifungal(OTC)
Felodipine Felodipine(RX) , Felodipine(RX) , Felodipine(RX)
Desmopressin Acetate Desmopressin Acetate(RX) , Desmopressin Acetate(RX) , Desmopressin Acetate(RX) , Desmopressin Acetate(RX) , Desmopressin Acetate(RX) , Desmopressin Acetate(RX)
Econazole Nitrate Econazole Nitrate(RX) , Econazole Nitrate(RX) , Econazole Nitrate(RX)
Verteporfin Visudyne(RX)
Spinosad Spinosad(RX) , Natroba(RX)
Amlodipine Besylate Amlodipine(RX)
Nicotine Rugby Nicotine Polacrilex Gum, Coated Cinnamon Flavor(OTC) , Preferred Plus Nicotine Polacrilex Gum, Original Flavor(OTC) , Nicotine Polacrilex, Original(OTC) , Nicotine Polacrilex Original Flavor(OTC) , Rugby Nicotine Polacrilex Gum, Original Flavor(OTC) , Nicotine(OTC)
Glipizide Glipizide(RX) , Glipizide(RX) , Glipizide(RX) , Glipizide(RX) , Glipizide(RX)
Crisaborole Eucrisa(RX)
Dutasteride Dutasteride(RX) , Dutasteride(RX)
Mirabegron Myrbetriq(RX) , Myrbetriq(RX) , Myrbetriq(RX)
Acetaminophen Acetaminophen(OTC) , Acephen(OTC)
Ondansetron Zuplenz(RX) , Zuplenz(RX)
Paliperidone Invega(RX) , Invega(RX) , Paliperidone(RX) , Paliperidone(RX) , Invega(RX) , Invega(RX) , Paliperidone(RX) , Invega(RX) , Paliperidone(RX) , Paliperidone(RX)
Alendronate Sodium , Cholecalciferol Fosamax Plus D(RX) , Fosamax Plus D(RX)
Ritonavir Norvir(RX)
Fidaxomicin Dificid(RX) , Dificid(RX)
Rosuvastatin Calcium Rosuvastatin Calcium(RX) , Rosuvastatin Calcium(RX)
Hydromorphone Hydrochloride Exalgo(RX) , Exalgo(RX) , Hydromorphone Hydrochloride Extended-Release(RX) , Exalgo(RX) , Exalgo(RX) , Hydromorphone Hydrochloride Extended-Release(RX)
Ketoconazole Nizoral A-D(OTC) , Xolegel(RX)
Ibuprofen Infants Advil(OTC) , Childrens Advil(OTC)
Azithromycin Azithromycin(RX)
Indomethacin Indomethacin(RX) , Indocin(RX)
Morphine Sulfate Arymo Er(RX) , Morphine Sulfate Extended-Release(RX)

Dosages

Route Formulation Per Unit Dose
Intramuscular Injection
Intravenous Injection
Intravenous Powder, For Injection Solution, Lyophilized
Intravenous Solution, Injection
Iv(infusion) Injection
Nasal Spray, Metered
Topical Aerosol
Topical Cream, Augmented
Topical Cream, Emulsion, Sustained Release
Topical Emulsion, Aerosol Foam
Topical Emulsion, Cream
Topical Gel
Topical Lotion
Topical Shampoo
Topical Solution
Transdermal Gel
Vaginal Emulsion, Cream
Buccal Gum, Chewing 0.21MG
Iv(infusion) Powder, For Injection Solution
Rectal Suppository 0.21MG
Topical Ointment
Topical Swab
Vaginal Suppository
Oral Solution, Liquid, Concentrate, Oral
Oral Capsule 0.2MG
Oral Capsule, Soft Gelatin 0.25MG
Oral Film, Soluble 0.06MG
Oral Tablet 0.4MG
Oral Tablet (immed./comp. Release), Film Coated 0.15MG
Oral Tablet, Coated
Oral Tablet, Controlled Release 0.21MG
Oral Tablet, Extended Release 0.11MG
Oral Tablet, Film Coated 0.36MG
Oral Tablet, For Suspension 0.1MG
Oral Tablet, Orally Disintegrating 0.21MG
Oral Tablet, Sustained Action 0.17MG
Oral Tablet, Sustained Action, Coated 0.24MG
Oral Solution

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Usage Over Time

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