GLUTAMIC ACID, DL-

Molecular Excipient

Mwt. LogP HBD HBA PSA RB CSP3
146.0 -4.1 1 4 108.0 4 0.6
UNII
61LJO5I15S
CAS
617-65-2
SYNONYMS
  • Glutaminic Acid
  • .alpha.-Aminoglutaric Acid
  • Glutamic Acid Dl-Form
  • (+/-)-Glutamic Acid
  • Glutamic Acid Dl-Form [mi]
  • Nsc-9967
  • Nsc-206301
ZINC ID(s)
Availability
Present in 95 ZINC catalogs

Known Active Genes

This compound has been observed to have activity at 10μM or less against the following gene(s).
Name Description Classification
MURI Glutamate racemase Enzyme / Enzyme-Other
GRIK2 Ionotropic glutamate receptor subunit GluR6(Q) Ion Channel / Lgic
GRIA2 Glutamate receptor 2 Ion Channel / Lgic
GRIK5 Glutamate receptor ionotropic, kainate 5 Ion Channel / Lgic
GRIK1 Glutamate receptor ionotropic, kainate 1 Ion Channel / Lgic
GRIK3 Glutamate receptor ionotropic, kainate 3 Ion Channel / Lgic
GRIA4 Glutamate receptor 4 Ion Channel / Lgic
GRIA1 Glutamate receptor 1 Ion Channel / Lgic
GRM1 Metabotropic glutamate receptor 1 Membrane Receptor / Gpcr-C
GRM3 Metabotropic glutamate receptor 3 Membrane Receptor / Gpcr-C
GRM8 Metabotropic glutamate receptor 8 Membrane Receptor / Gpcr-C
GRM2 Metabotropic glutamate receptor 2 Membrane Receptor / Gpcr-C
GRM4 Metabotropic glutamate receptor 4 Membrane Receptor / Gpcr-C
GRM5 Metabotropic glutamate receptor 5 Membrane Receptor / Gpcr-C
GRM6 Metabotropic glutamate receptor 6 Membrane Receptor / Gpcr-C

Clinical Trials

This compound has been an intervention in the following clincial trials (per clinicaltrials.gov).
Code Date Title Phase Status
NCT02002130 2015-01-01 The Use of Glutamic Acid Decarboxylase (GAD) and Gamma-Amino Butyric Acid (GABA) in the Treatment of Type I Diabetes Phase 1 Not Yet Recruiting
NCT01826045 2013-03-01 Efficacy and Safety Study of PGA (Poly-gamma Glutamic Acid) for Cervical Intraepithelial Neoplasia Phase 2 Recruiting
NCT01501942 2012-02-01 Efficacy, Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of Oral Administration of AIM-102 in Patients With Mild to Moderate Allergic Asthma Phase 2 Completed
NCT00369564 2007-05-01 Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer Phase 3 Completed
NCT00300040 2006-05-01 Safety/Feasibility Study of HBOC-201 in Amputation at/Below Knee From Critical Lower Limb Ischemia Phase 2 Terminated
NCT00301535 2006-02-01 A Study of HemopureĀ® to Enhance Tissue Preservation During Cardiopulmonary Bypass Surgery Phase 2 Recruiting
NCT00489827 2005-10-01 Glutamate for Metabolic Intervention in Coronary Surgery Phase 3 Active, Not Recruiting
NCT00213915 2004-02-01 L-Arginine Supplementation and Exercise; L-Arginine Supplementation and Renal Function Phase 4 Completed
NCT00069901 2003-02-01 Phase II CT-2103/Carboplatin in Ovarian Cancer Phase 2 Completed
NCT00357019 2001-04-01 Study of the Clinical and Biological Efficacity of NAAXIA SINEĀ® in Vernal Keratoconjunctivitis Phase 4 Completed
NCT00000768 1998-08-01 A Randomized Comparative Pharmacokinetic Study of Oral Ganciclovir After Treatment With Intravenous Ganciclovir for Cytomegalovirus Gastrointestinal Disease in AIDS Patients Phase 1 Completed

(Browse) Purchasable Analogs in ZINC

Dosages

Route Formulation Per Unit Dose
Vaginal Emulsion, Cream 0.1%

More Information

Usage Over Time

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