LACTIC ACID, DL-

Molecular Excipient

Mwt. LogP HBD HBA PSA RB CSP3
89.0 -1.9 1 3 60.0 1 0.67
UNII
3B8D35Y7S4
CAS
50-21-5
SYNONYMS
  • Dl-Lactic Acid
  • Lacticum Acidum
  • Racemic Lactic Acid
  • Ordinary Lactic Acid
  • (+/-)-2-Hydroxypropanoic Acid
  • (+/-)-Lactic Acid
  • Lacticum Acidum [hpus]
  • Dl-Lactic Acid [mi]
  • .alpha.-Hydroxypropanoic Acid
  • Tonsillosan
  • E 270
  • Lurex
  • Milk Acid
  • .alpha.-Hydroxypropionic Acid
  • Purac Fcc 80
  • Purac Fcc 88
  • Hipure 88
  • Dl- Lactic Acid [who-Dd]
  • Lactic Acid (+-)
  • Nsc-367919
  • E-270
  • Ins-270
  • Ins No.270
  • Lactic Acid [who-Ip]
  • Acidum Lacticum [who-Ip Latin]
ZINC ID(s)
Availability
Present in 87 ZINC catalogs

Known Active Genes

There has not been any activity reported at 10μM or less for this excipient (per ChEBML)

Clinical Trials

This compound has been an intervention in the following clincial trials (per clinicaltrials.gov).
Code Date Title Phase Status
NCT02240407 2016-01-01 Re-administration of Intramuscular AAV9 in Patients With Late-Onset Pompe Disease Phase 1 Not Yet Recruiting
NCT02048943 2015-03-01 Dovitinib Lactate, Gemcitabine Hydrochloride, and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced Solid Tumors or Pancreatic Cancer Phase 1 Withdrawn
NCT02327611 2015-02-01 CUstodiol Versus RInger: whaT Is the Best Agent? Phase 4 Recruiting
NCT02349516 2015-02-01 Squalamine Lactate Eye Drops in Combination With Ranibizumab in Patients With Diabetic Macular Edema (DME) Phase 2 Not Yet Recruiting
NCT01313533 2015-01-01 Biologically Modified Saphenous Vein Transplants for Improved CABG Outcomes Phase 1/Phase 2 Not Yet Recruiting
NCT02208804 2014-11-01 Surefire Infusion System vs. Standard Microcatheter Use During Holmium-166 Radioembolization Phase 2/Phase 3 Recruiting
NCT02108782 2014-10-01 Dovitinib Lactate in Treating Patients With Pancreatic Neuroendocrine Tumors Phase 2 Active, Not Recruiting
NCT02314429 2014-09-01 Trial Evaluating the Safety of a Lactate Releasing Vaginal Ring for the Prophylaxis of Bacterial Vaginosis Phase 1 Recruiting
NCT02270723 2014-08-01 The Effect of Human Albumin on Coagulation Competence and Hemorrhage Phase 4 Enrolling By Invitation
NCT02042287 2014-06-01 Treatment Comparison of Antibiotics Versus Vaginal Lactic Acid in Non-pregnant Women With Acute Symptomatic Bacterial Vaginosis Phase 4 Recruiting
NCT01048138 2014-03-01 Use of Biperiden for the Prevention of Post-traumatic Epilepsy Phase 3 Recruiting
NCT02050048 2014-01-01 High Volume Lactated Ringer's Solution and Pancreatitis Phase 2/Phase 3 Recruiting
NCT01988558 2013-12-01 A Phase I/II to Assess Safety, Tolerability and Efficacy of DL-lactic Acid Syrup in Children With Recurrent Tonsillitis Phase 1/Phase 2 Recruiting
NCT01337934 2013-10-01 Lactated Ringer Versus Albumin in Early Sepsis Therapy Phase 3 Recruiting
NCT01980459 2013-10-01 Magnesium Treatment of Inflammation in Disorders of Glucose Homeostasis Phase 2/Phase 3 Recruiting
NCT02003833 2013-09-01 Poly-L-lactic Acid for Skin Quality Phase 4 Active, Not Recruiting
NCT01692769 2013-05-01 Trial Of Normal Saline Versus Ringer's Lactate In Paediatric Trauma Patients Phase 4 Recruiting
NCT01807702 2013-03-01 13C-Pyruvate Breath Test Phase 1 Completed
NCT01770912 2013-03-01 Efficacy of Steroid Supplementation After TMJ Rinsing for Pain Management Phase 2 Recruiting
NCT01769183 2013-02-01 Squalamine for the Treatment in Proliferative Diabetic Retinopathy Phase 2 Completed
NCT01587963 2013-02-01 High Dose Vitamin C in the Critically Ill Patient Phase 2 Active, Not Recruiting
NCT02064075 2013-02-01 The Mortality and Changes in Quality of Life of Patients Suffering From SAH With Different Hydration Strategies Phase 4 Completed
NCT01678963 2012-11-01 Efficacy and Safety of Squalamine Lactate Eye Drops in Subjects With Neovascular (Wet) Age-related Macular Degeneration (AMD) Phase 2 Active, Not Recruiting
NCT01515969 2012-07-01 Phase I Erlotinib and Dovitinib (TKI258) in Advanced Non-small Cell Lung Cancer (NSCLC) Phase 1 Suspended
NCT01779193 2012-06-01 Probiotics Capsule as Supplemental Therapy for Group B Streptococci Infection and Vaginitis During Pregnancy Phase 4 Recruiting
NCT01556022 2012-06-01 Safety and Feasibility Trial of Adipose-Derived Regenerative Cells in the Treatment of Chronic Myocardial Ischemia Phase 2 Active, Not Recruiting
NCT01497392 2012-03-01 Dovitinib Lactate, Gemcitabine Hydrochloride, and Capecitabine in Treating Patients With Advanced or Metastatic Solid Tumors, Pancreatic Cancer and Biliary Cancers Phase 1 Active, Not Recruiting
NCT01573507 2012-03-01 Lactate Therapy After Traumatic Brain Injury Phase 2 Recruiting
NCT01524913 2012-01-01 A Double Blind Study Comparing Hyaluronic Acid, Corticosteroid and Placebo During Arthrocentesis for TMJ Phase 4 Active, Not Recruiting
NCT01473290 2011-12-01 Probiotic Therapy in Preventing Gastrointestinal Complications in Patients Undergoing Chemotherapy and Pelvic Radiation Therapy Phase 3 Not Yet Recruiting
NCT01591993 2011-10-01 Determination of Sensitive Skin and Its Biophysical Response in a Latin-American Population Phase 4 Completed
NCT01473537 2011-10-01 Optimised Fluoride Prevention by Double Rinse With Fluoride and Calcium Phase 1 Completed
NCT01444508 2011-09-01 Effect of Colloid Versus Crystalloid on Coagulation Phase 4 Recruiting
NCT02009033 2011-09-01 Effect of Colloid Versus Crystalloid on Coagulation in Elective Urological Surgery Phase 4 Completed
NCT01387477 2011-06-01 Lactate and Hypoglycemia Phase 4 Recruiting
NCT01428050 2011-05-01 The Use of a Restrictive Fluid Regimen With Hypertonic Saline for Patients Undergoing Pancreaticoduodenectomy Phase 2 Recruiting
NCT01333670 2011-04-01 Efficacy of Prontosan Solution on Chronic Ulcers Phase 3 Completed
NCT01307865 2011-01-01 Volume Restoration of the Aging Midface With Sculptra Aesthetic Phase 4 Completed
NCT01250886 2010-12-01 Acid-base Balance in Patients Undergoing Colonoscopy Phase 1 Enrolling By Invitation
NCT01236833 2010-11-01 Lactated Ringer's Solution in Neonates With Feeding Intolerance Phase 2 Active, Not Recruiting
NCT01126606 2010-08-01 Comparative Safety and Efficacy Evaluation Between Dermacyd Silver and Glycerine Vegetal Soap Granado Traditional Phase 3 Completed
NCT01158365 2010-07-01 Dermacyd in Odor Reducing. Phase 3 Completed
NCT01575600 2010-07-01 Effect of Intravenous Fluid Therapy on Postoperative Vomiting in Children Undergoing Otorhinolaryngological Surgery Phase 3 Completed
NCT01116102 2010-05-01 Study of In-line Pressure Using Various Techniques of Subcutaneous Administration of Fluids Enabled by Human Recombinant Hyaluronidase (INFUSE-AT1A) Phase 4 Terminated
NCT01031784 2009-12-01 Radioactive Holmium Microspheres for the Treatment of Liver Metastases Phase 1 Completed
NCT01004198 2009-12-01 Phase IIa Study of MP4OX in Traumatic Hemorrhagic Shock Patients Phase 2 Completed
NCT01981655 2009-12-01 0.5M Na Lactate Solution in Acute Heart Failure (AHF) Phase 2 Completed
NCT01012648 2009-11-01 Early Fluid Resuscitation With Balanced HES 130/0.4 [6%] in Severe Burn Injury Phase 4 Recruiting
NCT00991627 2009-09-01 Different Approaches to Maternal Hypotension During Cesarean Section Phase 4 Completed
NCT00981305 2009-09-01 Impact of Lactate-Containing Vaginal Lubricant on Sexual Dysfunction in Young Breast Cancer Survivors Phase 3 Active, Not Recruiting
NCT01433276 2009-07-01 Efficacy, Safety of Solution Containing Hyperosmolar Sodium Lactate Infusion for Resuscitation of Patients With Hemorrhagic Shock Phase 3 Completed
NCT00932945 2009-06-01 Dermacyd PH_DESILSTY_FR (Lactic Acid) - Acceptability - Stay on Frutal Phase 3 Completed
NCT00933257 2009-06-01 Dermacyd PH_DESILSTY_FR (Lactic Acid) - Photo Evaluation - Stay on Frutal Phase 3 Completed
NCT00933699 2009-06-01 Dermacyd PH_DESILSTY_FL (Lactic Acid) - Acceptability - Stay on Floral. Phase 3 Completed
NCT00933712 2009-06-01 Dermacyd Silver Floral (Lactic Acid) - Compatibility. Phase 3 Completed
NCT00933946 2009-06-01 Dermacyd Silver Frutal (Lactic Acid) - Compatibility. Phase 3 Completed
NCT00933842 2009-06-01 Dermacyd PH_DESILSTY_FL (Lactic Acid) - Photo Evaluation - Stay on Floral Phase 3 Completed
NCT00933907 2009-06-01 Dermacyd PH_DESILSTY_FR (Lactic Acid) - Compatibility - Stay on Frutal Phase 3 Completed
NCT00933413 2009-06-01 Dermacyd Silver Frutal (Lactic Acid) - Acceptability. Phase 3 Completed
NCT00933504 2009-06-01 Dermacyd Silver Floral (Lactic Acid) - Compatibility - Stay on Floral Phase 3 Completed
NCT00933569 2009-06-01 Dermacyd Silver Floral (Lactic Acid) - Acceptability. Phase 3 Completed
NCT00932984 2009-06-01 Dermacyd Silver Floral (Lactic Acid) - Photo Evaluation Phase 3 Completed
NCT00933075 2009-06-01 Dermacyd Silver Frutal (Lactic Acid) - Photo Evaluation. Phase 3 Completed
NCT00995683 2009-06-01 Preventive Sodium Lactate and Traumatic Brain Injury Phase 2/Phase 3 Completed
NCT00431743 2009-04-01 Fluid Infusion During Breast Surgery Phase 4 Not Yet Recruiting
NCT00869687 2009-03-01 Biopsy Study for Sculptra (Poly-L-Lactic Acid) Phase 2 Completed
NCT00881270 2009-03-01 Dermacyd Infantile - Acceptability. Phase 4 Completed
NCT00881374 2009-02-01 Dermacyd Infantile (Lactic Acid)- Compatibility. Phase 4 Completed
NCT00881348 2009-02-01 Dermacyd Infantile (Lactic Acid) - Photo Evaluation. Phase 4 Completed
NCT01111123 2009-01-01 Ammonium Lactate Lotion 12% (Lac-hydrin®) and Halobetasol Propionate Ointment 0.05% (Ultravate®) in the Treatment and Maintenance of Psoriasis Phase 4 Completed
NCT00797589 2009-01-01 Effect of Prime Solution on Fluid Balance After Open Heart Surgery Phase 4 Recruiting
NCT00807885 2008-12-01 Study of Techniques of Subcutaneous Administration of Fluids Enabled by Human Recombinant Hyaluronidase Phase 4 Completed
NCT01431612 2008-11-01 Effects of Adrenergic Drugs on the Fluid Balance During Surgery Phase 1/Phase 2 Completed
NCT00794612 2008-11-01 Dermacyd Femina Pocket BR (Lactic Acid)- Acceptability. Phase 3 Completed
NCT00793026 2008-11-01 Dermacyd Breeze Pocket BR (Lactic Acid) - Acceptability Phase 3 Completed
NCT00783640 2008-10-01 Dermacyd Femina (Lactic Acid) Pocket BR - Photo Evaluation Phase 3 Completed
NCT00784121 2008-10-01 Dermacyd Breeze (Lactic Acid) Pocket BR - Compatibility Phase 3 Completed
NCT00783861 2008-10-01 Dermacyd Femina (Lactic Acid) Pocket BR - Compatibility Phase 3 Completed
NCT00784069 2008-10-01 Dermacyd Breeze (Lactic Acid) Pocket BR - Photo Evaluation Phase 3 Completed
NCT00795327 2008-10-01 Injectable POLY-L-Lactic Acid for Treatment of Hill and Valley Acne Scarring Phase 4 Completed
NCT00783939 2008-09-01 Dermacyd PH_DETINBACK Tangerine Mix (Lactic Acid) - Safety. Phase 3 Completed
NCT00785148 2008-08-01 Dermacyd PH_DETINLYN Sweet Flower (Lactic Acid) - Safety Phase 3 Completed
NCT00785850 2008-08-01 Dermacyd PH_DETINBACK (Lactic Acid) Sweet Flower - Safety. Phase 3 Completed
NCT00783666 2008-08-01 Dermacyd PH_DETINBACK Tangerine Mix (Lactic Acid) - Photo Evaluation Phase 3 Completed
NCT00785590 2008-08-01 Dermacyd PH_DETINLYN (Lactic Acid) Sweet Flower - Photo Evaluation. Phase 3 Completed
NCT00784056 2008-08-01 Dermacyd PH_DETINLYN Tangerine Mix (Lactic Acid) - Photo Evaluation Phase 3 Completed
NCT00785642 2008-08-01 Dermacyd PH_DETINLYN Tangerine Mix (Lactic Acid) - Safety. Phase 3 Completed
NCT00785720 2008-08-01 Dermacyd PH_DETINBACK (Lactic Acid) Sweet Flower - Photo Avaluation Phase 3 Completed
NCT00785655 2008-07-01 Dermacyd PH_DETINLYN (Lactic Acid) Sweet Flower - Compatibility Phase 3 Completed
NCT00786097 2008-07-01 Dermacyd PH_DETINLYN (Lactic Acid) Tangerine Mix - Compatibility Phase 3 Completed
NCT00784160 2008-07-01 Dermacyd PH_DETINBACK Tangerine Mix (Lactic Acid)- Compatibility Phase 3 Completed
NCT01654653 2008-07-01 Efficacy and Safety of Hypertonic Sodium Lactate Solution Compared With 6% HES Solution in CABG Patients Phase 4 Completed
NCT00785681 2008-07-01 Dermacyd PH_DETINBACK (Lactic Acid) Sweet Flower - Compatibility Phase 3 Completed
NCT00712868 2008-06-01 Acceptability of Lactacyd Femina Phase 4 Completed
NCT00694343 2008-06-01 Efficacy of Voluven® for the Prevention of Hypotension During Spinal Anesthesia for Cesarean Section Phase 4 Completed
NCT00966628 2008-05-01 Effect of Hypertonic Sodium Lactate on sVCAM-1 Level as Surrogate Marker of Endothelial Capillary Leakage in Pediatric Dengue Shock Syndrome Patients (DSS) Phase 3 Active, Not Recruiting
NCT00761800 2008-05-01 Dermacyd Teen Care Tangerina Mix - Compatibility Phase 3 Completed
NCT00705744 2008-04-01 Dermacyd Femina (Lactic Acid) - Photo Dermatological Evaluation of the Irritation and Sensitivity Potential. Phase 3 Completed
NCT01108601 2008-04-01 Transtympanic Ringer's Lactate for the Prevention of Cisplatin Ototoxicity Phase 1/Phase 2 Recruiting
NCT00705276 2008-04-01 Dermacyd Femina Delicata (Lactic Acid)- Photo Dermatological Evaluation of the Irritation and Sensitivity Potential Phase 3 Completed
NCT00679562 2008-03-01 Lactacyd Radiance (Lactic Acid) Prophetic Patch Test Phase 2 Completed
NCT00668486 2008-01-01 Dermacyd Delicata Breeze - Photo Evaluation Phase 3 Completed
NCT00801359 2008-01-01 BSSPlus Versus Lactated Ringer's for Phacoemulsification Phase 2 Completed
NCT00664391 2008-01-01 Safety Dermatological Evaluation: Acceptability With Gynecological Follow up - Dermacyd Breeze Phase 3 Completed
NCT00663273 2007-12-01 Safety Dermatological Evaluation: Acceptability With Gynecological Follow up - Dermacyd Tina Gel Sweet Flower Phase 3 Completed
NCT00668226 2007-12-01 Dermacyd Delicata Pocket BR - Photo Evaluation Phase 3 Completed
NCT00663325 2007-12-01 Safety Dermatological Evaluation: Acceptability With Gynecological Follow up - Dermacyd Tina Gel Sweet Flower Phase 3 Completed
NCT00669058 2007-12-01 Dermatological Evaluation of Topic Compatibility-Dermacyd Tina Gel Tangerina Mix Phase 3 Completed
NCT00668577 2007-12-01 Dermatological Evaluation of Topic Compatibility - Dermacyd Breeze Phase 3 Completed
NCT00668668 2007-12-01 Dermatological Evaluation of Topic Compatibility-Dermacyd Tina Gel Sweet Flower Phase 3 Completed
NCT00663390 2007-12-01 Safety Dermatological Evaluation: Acceptability With Gynecological Follow up - Dermacyd Delicata Pocket BR Phase 3 Completed
NCT00668460 2007-11-01 Dermatological Evaluation of Topic Compatibility-Dermacyd Delicata Pocket BR Phase 3 Completed
NCT00668629 2007-11-01 Dermacyd Tina Gel Sweet Flower - Photo Evaluation Phase 3 Completed
NCT00860704 2007-11-01 Goal Directed Fluid Therapy Phase 4 Recruiting
NCT00668889 2007-11-01 Dermacyd Tina Gel Tangerina Mix - Photo Evaluation Phase 3 Completed
NCT00549419 2007-10-01 Arterial Pressure Based Cardiac Output for Goal-Directed Therapy in Abdominal Surgery Phase 4 Completed
NCT00487474 2007-06-01 A Single-Center, Open-Label, Exploratory Study of the Volumizing Effect of SCULPTRA Measured by Three Dimensional Digital Surface Imaging Phase 4 Completed
NCT00467922 2007-05-01 An Assessment of Goal-Directed Intraoperative Fluid Management in Hand Assisted Laparoscopic Colectomy Phase 3 Completed
NCT00447551 2007-01-01 Canadian Aesthetic Experience With Sculptra Therapy Phase 4 Completed
NCT01310790 2006-10-01 Strategy of Early Improvement of Tissue Oxygenation Decrease the Mortality of Severe Sepsis and Septic Shock Phase 4 Completed
NCT00542516 2006-09-01 Comparison Between Two Techniques of Volemic Expansion in Hip Replacement Arthroplasty Phase 4 Completed
NCT00517127 2006-09-01 Crystalloids Versus Colloids During Surgery Phase 4 Recruiting
NCT00584155 2006-07-01 Protection From Cisplatin Ototoxicity by Lactated Ringers Phase 1 Completed
NCT01388907 2006-05-01 Efficacity Assessment of PREVADH® in Adhesion Prevention in Gynaecologic Surgery Phase 4 Completed
NCT00333476 2006-05-01 "A Study of MSI-1256F (Squalamine Lactate) To Treat ""Wet"" Age-Related Macular Degeneration" Phase 2 Terminated
NCT00270673 2006-02-01 Early Lactate-Directed Therapy in the Intensive Care Unit (ICU) Phase 3 Completed
NCT00282620 2006-01-01 Magnesium to Reduce Implantable Cardioverter Defibrillator (ICD) Shocks and Improve Patient's Quality of Life. Phase 4 Recruiting
NCT00282659 2006-01-01 The Use of Magnesium to Improve Blood Pressure, Cholesterol, and Glucose Control Phase 4 Recruiting
NCT00126308 2005-11-01 Facial Lipoatrophy Trial: Immediate Versus Deferred Injections of Poly-L-Lactic Acid for HIV Facial Lipoatrophy Phase 4 Terminated
NCT00360932 2005-10-01 "Facial Lipoatrophy Correction Experience With SCULPTRA (""FACES"" Study)" Phase 4 Completed
NCT00529711 2005-07-01 The Efficacy of Hypertonic Lactate Solution in CABG(Coronary Artery Bypass Grafting) Patients Phase 3 Completed
NCT00425334 2005-07-01 Safety Study of Hemospan® in Prostatectomy Patients Phase 2 Completed
NCT00139282 2005-06-01 "A Safety and Efficacy Study of Squalamine Lactate for Injection (MSI-1256F) for ""Wet"" Age-Related Macular Degeneration" Phase 3 Terminated
NCT00094120 2004-10-01 "MSI-1256F (Squalamine Lactate) in Combination With Verteporfin in Patients With ""Wet"" Age-Related Macular Degeneration (AMD)" Phase 2 Terminated
NCT00444353 2004-08-01 DL6049 Versus Cosmoplast in the Treatment of Nasolabial Fold Wrinkles, Long Term Follow-up Phase 3 Completed
NCT00089830 2004-08-01 "A Safety and Efficacy Study of MSI-1256F (Squalamine Lactate) To Treat ""Wet"" Age-Related Macular Degeneration" Phase 2 Terminated
NCT00444210 2004-06-01 DL6049 vs CosmoPlast in the Treatment of Nasolabial Fold Wrinkles Phase 3 Completed
NCT01632046 2004-03-01 Administration of pH-Neutral Peritoneal Dialysis Solutions Containing Lactate or Bicarbonate in Children Phase 4 Completed
NCT00319345 2003-11-01 Sodium-Lactate and Traumatic Brain Injury Phase 2/Phase 3 Terminated
NCT00135473 2003-04-01 Efficacy of Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP Trial) Phase 3 Completed
NCT00494949 2003-04-01 Increasing Dose Safety Study of Hemospan in Orthopedic Surgery Patients Phase 1/Phase 2 Completed
NCT00270192 2002-05-01 Antenatal Educational Intervention for Improvement of Breastfeeding Phase 3 Completed
NCT00529490 2002-03-01 Efficacy, Safety of Hypertonic Lactate Soln. as Fluid Resuscitation Compared With Ringer's Lactate in Post-CABG Pats Phase 3 Completed
NCT00244920 2002-01-01 Hormone Therapy With or Without Squalamine Lactate in Treating Patients Who Are Undergoing a Radical Prostatectomy for Locally Advanced Prostate Cancer Phase 2 Withdrawn
NCT00021385 2001-05-01 Squalamine Lactate Plus Carboplatin in Treating Patients With Recurrent or Refractory Stage III or Stage IV Ovarian Cancer Phase 2 Active, Not Recruiting

(Browse) Purchasable Analogs in ZINC

Dosages

Route Formulation Per Unit Dose
Im - Iv Injection
Intramuscular Injection
Intravenous Injection 0.13%
Iv(infusion) Injection 0.03%
Topical Solution 7.4%
Vaginal Suppository
Oral Liquid 0.2%

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