RIBOFLAVIN

Molecular Excipient

Mwt. LogP HBD HBA PSA RB CSP3
376.0 -1.7 5 9 162.0 5 0.41
CAS
83885
UNII
TLM2976OFR
SYNONYMS
ZINC ID(s)
Availability
Present in 76 ZINC catalogs

Known Active Genes

This compound has been observed to have activity at 10μM or less against the following gene(s).
Name Description Classification
RBP_CHICK Riboflavin-binding protein Unclassified / Unclassified

Clinical Trials

This compound has been an intervention in the following clincial trials (per clinicaltrials.gov).
Code Date Title Phase Status
NCT02276989 2015-03-01 Evaluation of a Compliance Marker in Prescription Opioid Abusers With Chronic Pain Phase 2 Not Yet Recruiting
NCT02095730 2014-05-01 Corneal Cross-Linking Comparing Variables Phase 3 Not Yet Recruiting
NCT01972854 2013-11-01 A Multi-Center, Randomized, Placebo-Controlled Evaluation of the Safety and Efficacy of the KXL System With VibeX (Riboflavin Ophthalmic Solution) for Corneal Collagen Cross-Linking in Eyes With Keratoconus Phase 3 Active, Not Recruiting
NCT02009709 2013-10-01 Study of the Safety and Effectiveness of Collagen Cross-Linking at an Irradiance of 9 mW/cm2 and 18 mW/cm2 Phase 1 Recruiting
NCT01893359 2013-08-01 Safety and Efficacy of Corneal Collagen Cross-linking Following LASIK for Treatment of Hyperopia and Hyperopic Astigmatism Phase 1/Phase 2 Active, Not Recruiting
NCT01741558 2013-04-01 The Effects of mETHotrexate Therapy on ST Segment Elevation MYocardial InfarctionS (TETHYS Trial) Phase 2 Not Yet Recruiting
NCT01956474 2013-01-01 A Study of Collagen Crosslinking With Ultraviolet-A in Asymmetric Corneas Phase 4 Recruiting
NCT01672814 2012-08-01 Microwave Treatment and Corneal Collagen Crosslinking for Keratoconus Phase 3 Recruiting
NCT01643252 2012-07-01 Safety and Efficacy Study for Corneal Collagen Cross-Linking in Eyes With Corneal Ectasia After Refractive Surgery Phase 3 Withdrawn
NCT01459679 2012-07-01 A Multi-Center, Randomized, Controlled Evaluation of the Safety and Efficacy of the KXL System With VibeX (Riboflavin Ophthalmic Solution) for Corneal Collagen Cross-Linking in Eyes With Keratoconus or Corneal Ectasia After Refractive Surgery Phase 3 Active, Not Recruiting
NCT01643226 2012-07-01 Safety and Efficacy Study of Corneal Collagen Cross-Linking in Eyes With Keratoconus Phase 3 Active, Not Recruiting
NCT01344187 2012-07-01 Safety and Efficacy Study of Corneal Collagen Cross-Linking in Eyes With Keratoconus Phase 3 Active, Not Recruiting
NCT01582880 2012-03-01 Use of Cross-linked Donor Corneas as Carriers for the Boston Keratoprosthesis Phase 1/Phase 2 Recruiting
NCT01464268 2011-11-01 Transepithelial Corneal Collagen Crosslinking for Keratoconus and Corneal Ectasia Phase 3 Recruiting
NCT01325298 2011-03-01 UVA-Riboflavin Crosslinking Treatment of Corneal Ectasia Phase 2 Recruiting
NCT01398839 2010-12-01 Safety Study of the VEGA UV-A System to Treat Ectasia Phase 3 Terminated
NCT01398852 2010-12-01 Safety and Effectiveness Study of the VEGA UV-A System for Cross-linking in Eyes With Keratoconus and Ectasia Phase 3 Terminated
NCT01381354 2010-10-01 Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS) Phase 1 Active, Not Recruiting
NCT01190306 2010-08-01 Safety Study of the VEGA UV-A System to Treat Keratoconus Phase 3 Terminated
NCT01152541 2010-06-01 Corneal Collagen Crosslinking for Progressive Keratoconus and Ectasia Using Riboflavin/Dextran and Hypotonic Riboflavin Phase 3 Recruiting
NCT01112072 2010-04-01 Corneal Collagen Crosslinking and Intacs for Keratoconus and Ectasia Phase 3 Recruiting
NCT01485211 2010-01-01 Corneal Thickness Changes During Corneal Collagen Cross-linking With Ultraviolet-A Irradiation and Riboflavin Phase 4 Completed
NCT01081561 2009-06-01 Collagen Cross-Linking for Keratoconus/Ectasia With and Without Intacs Phase 2/Phase 3 Recruiting
NCT02068430 2008-11-01 Safety and Effectiveness of the UV-X System for Corneal Collagen Cross-Linking in Eyes With Refractory Corneal Infection Phase 1 Recruiting
NCT00841386 2008-09-01 Treatment of Keratoconus Using Collagen Cross-Linking Phase 2/Phase 3 Recruiting
NCT00815256 2008-08-01 Safety and Effectiveness of Collagen Cross Linking in Progressive Mild and Moderate Keratoconus Phase 3 Recruiting
NCT00679666 2008-04-01 Corneal Crosslinking in Keratoconus and Corneal Ectasia Phase 2/Phase 3 Withdrawn
NCT00674661 2007-12-01 Corneal Collagen Cross-Linking for Ectasia (CXL) Phase 3 Completed
NCT00647699 2007-12-01 Corneal Collagen Cross-linking for Progressive Keratoconus Phase 3 Completed
NCT00220532 2005-07-01 Folate and Protection Against Cervical Cancer Phase 1/Phase 2 Terminated
NCT00202228 2002-07-01 Lactate Metabolism Study in HIV Infected Persons Phase 4 Completed
NCT00143702 2001-08-01 D4T or Abacavir Plus Vitamin Enhancement in HIV-Infected Patients (DAVE) Phase 2/Phase 3 Completed

(Browse) Purchasable Analogs in ZINC

Regulatory Status of Riboflavin

Gras - Generally recognized as safe.

Dosages

Route Formulation Per Unit Dose
Oral Tablet 0.03MG

More Information

Usage Over Time

Comments