TOCOPHEROL

Molecular Excipient

Mwt. LogP HBD HBA PSA RB CSP3
417.0 8.5 1 2 29.0 12 0.79
UNII
R0ZB2556P8
CAS
1406-66-2
SYNONYMS
  • Tocopherol
  • Mixed Tocopherols 95
  • Oristar Mixed Tocopherols
  • Covi-Ox T 50 C
  • Covi-Ox T 70 C
  • Tocopherol [inci]
  • Tocopherols
  • Tocopherol [ii]
  • E-306
  • Tocopherols (mixed)
  • Tocopherol [who-Dd]
  • Tocopherol [vandf]
  • Mixed Tocopherols
ZINC ID(s)
Availability
Present in 7 ZINC catalogs

Known Active Genes

There has not been any activity reported at 10μM or less for this excipient (per ChEBML)

Clinical Trials

This compound has been an intervention in the following clincial trials (per clinicaltrials.gov).
Code Date Title Phase Status
NCT02368457 2015-02-01 Management of Mandibular ORN: PENTO as Medical Treatment Phase 4 Recruiting
NCT02251041 2014-09-01 Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers (CAPITL) Phase 2 Recruiting
NCT02104505 2014-07-01 Effect of Gamma Tocopherol Enriched Supplementation on Response to Inhaled LPS Phase 1/Phase 2 Recruiting
NCT01886443 2013-08-01 Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers Phase 1 Completed
NCT01457690 2011-10-01 Study of the Absorption of Vitamin E Water-soluble Form (Pegylated) in the Familial Hypocholesterolemia With Chylomicron Retention Phase 3 Active, Not Recruiting
NCT01291433 2011-03-01 Trial of Combined Pentoxifylline-tocopherol-clodronate vs Placebo in Radiation-induced Brachial Plexopathy Phase 3 Recruiting
NCT01314443 2011-01-01 Impact of Smoking Cessation and γ-Tocopherol to Restore Vascular Endothelial Function Phase 1/Phase 2 Completed
NCT01329770 2010-12-01 Safety and Efficacy Study of Antioxidants for the Treatment of the Fragile X Syndrome Phase 2 Active, Not Recruiting
NCT01822405 2010-07-01 Treatment of Radiation-induced Fibrosis in the Upper Aerodigestive Tract Cancer by a Combination of Pentoxifylline-tocopherol and Hyperbaric Oxygen Phase 2 Recruiting
NCT01574313 2010-04-01 Effect of Stellate Ganglion Block on Meniere's Disease Phase 4 Completed
NCT01061320 2010-01-01 Efficacy of Alpha Tocopherol for Prevention of Contrast-induced Nephropathy in Chronic Kidney Disease (CKD) Patients Phase 3 Enrolling By Invitation
NCT00836368 2008-12-01 In Vitro Basophil Responsiveness to Allergen Challenge After Gamma-tocopherol Supplementation in Allergic Asthmatics Phase 1 Completed
NCT00631085 2008-05-01 Effect of Gamma Tocopherol Supplementation on Neutrophil Response to 20,000 EU of Clinical Center Reference Endotoxin in Normal Adults Phase 1 Completed
NCT01544192 2008-04-01 Impact of Oral Versatile Antioxidants on Glaucoma Progression Phase 3 Completed
NCT00235716 2007-08-01 A Randomized, Clinical Trial of Vitamin E and Memantine in Alzheimer's Disease Phase 3 Completed
NCT00466596 2007-03-01 Effect of House Dust Mite Allergen Challenge in Persons Using 1200 mg Gamma Tocopherol Supplements Phase 1 Completed
NCT00386178 2006-10-01 Safety Study of a Vitamin E Supplement in Normal Volunteers and Those With Both Allergy and Asthma Phase 1 Completed
NCT00237718 2006-04-01 Provision of Antioxidant Therapy in Hemodialysis (PATH) Study Phase 2 Completed
NCT00678834 2006-03-01 Human Tissue Distribution of Orally Supplemented Natural Vitamin E Tocotrienol Phase 0 Completed
NCT00308971 2006-03-01 Tocopherols and Alpha Lipoic Acid Treatment Chronic Kidney Disease (TALAT) Phase 2 Completed
NCT00162526 2005-12-01 Tocopherol is a Novel Treatment for Cancer Related Mucositis Phase 2 Withdrawn
NCT00655018 2003-01-01 Effect of Vitamin E on Pediatric Nonalcoholic Fatty Liver Disease (NAFLD) Phase 2/Phase 3 Completed
NCT00188669 2002-07-01 The Use of Pentoxifylline and Vitamin E in the Treatment of Chronic Breast Pain Phase 2 Terminated
NCT00188552 2002-07-01 The Use of Pentoxifylline and Vitamin E in the Treatment of Late Radiation Related Injuries Phase 2 Terminated
NCT00119119 2002-02-01 Efficacy and Safety of Pentoxyphilline and Tocopherol on the Fibrosis in Patients With Chronic Hepatitis C Phase 3 Terminated
NCT00410449 2001-05-01 Oxidative Stress and Hemodialysis Access Failure Phase 4 Completed
NCT01594346 2000-09-01 Multicenter Vitamin E Trial in Aging Persons With Down Syndrome Phase 3 Completed
NCT00114387 1996-07-01 VEAPS: Vitamin E Atherosclerosis Prevention Study Phase 2/Phase 3 Completed
NCT01422317 1995-09-01 Effects of High-dose n-3 Fatty Acids on Clinical Outcome and Serum Lipids - Omacor Following Acute Myocardial Infarction Phase 3 Completed
NCT00169845 1994-10-01 Beta-carotene and Alpha-tocopherol Chemoprevention of Second Primary Malignancies in Head and Neck Cancer Patients Phase 3 Active, Not Recruiting
NCT00002586 1993-01-01 13-Cis Retinoic Acid With or Without Vitamin E for Prevention of Lung Cancer Phase 2 Completed

(Browse) Purchasable Analogs in ZINC

Products Using Tocopherol

Download
APIs Products incorporating these APIs
Icosapent Ethyl Vascepa(RX)
Isotretinoin Myorisan(RX) , Myorisan(RX)

Dosages

Route Formulation Per Unit Dose
Topical Ointment
Oral Capsule
Oral Tablet 0.08MG

More Information

Usage Over Time

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